氮杂二苯并环辛炔胺

更新时间：2024-01-04 16:49:58

氮杂二苯并环辛炔胺结构式	常用名	氮杂二苯并环辛炔胺	英文名	DBCO-Amine
	CAS号	1255942-06-3	分子量	276.33200
	密度	N/A	沸点	N/A
	分子式	C₁₈H₁₆N₂O	熔点	N/A
	MSDS	中文版美版	闪点	N/A

氮杂二苯并环辛炔胺用途

DBCO-amine 是一种可降解 (cleavable) 的 ADC 连接桥,用于抗体药物结合物 (ADCs) 的合成。

中文名	氮杂二苯并环辛炔胺
英文名	Azadibenzocylooctyne-amine
中文别名	氨基丙酰氮杂二苯并环辛炔
英文别名	更多

描述	DBCO-amine 是一种可降解 (cleavable) 的 ADC 连接桥,用于抗体药物结合物 (ADCs) 的合成。
相关类别	研究领域 >> 癌症信号通路 >> 抗体- 药物偶联物 >> ADC连接器
靶点	Cleavable
体外研究	ADC由抗体组成,抗体通过ADC连接物连接ADC细胞毒素。
参考文献	[1]. Ermira Pazolli, et al. Splicing modulator antibody-drug conjugates and methods of use. WO2019232449A1.

分子式	C₁₈H₁₆N₂O
分子量	276.33200
精确质量	276.12600
PSA	46.33000
LogP	3.04710
储存条件	-20°C

危险品运输编码	NONH for all modes of transport

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Visualizing metabolically labeled glycoconjugates of living cells by copper-free and fast huisgen cycloadditions.

Angew. Chem. Int. Ed. Engl. 47 , 2253-2255, (2008)