甲氧西林钠

• 常用名: 甲氧西林钠
• 英文名: Methicillin SodiuM
• CAS号: 132-92-3
• 分子量: 402.39700
• 密度: N/A
• 沸点: 640ºC at 760 mmHg
• 分子式: C₁₇H₁₉N₂NaO₆S
• 熔点: 196-197℃
• 闪点: 340.9ºC

甲氧西林钠用途

Meticillin钠盐是青霉素类的窄谱β内酰胺抗生素, 可治疗革兰氏阳性菌感染, 有效对抗β-内酰胺酶产生的微生物如金黄色葡萄球菌。

甲氧西林钠名称

• 中文名: 甲氧西林钠
• 英文名: methicillin sodium

甲氧西林钠生物活性

• 描述: Methicillin是β-内酰胺抗生素,其通过抑制参与肽聚糖合成的青霉素结合蛋白起作用。
• 相关类别:
  信号通路 >> 抗感染 >> 细菌
  研究领域 >> 感染

甲氧西林钠物理化学性质

• 沸点: 640ºC at 760 mmHg
• 熔点: 196-197℃
• 分子式: C₁₇H₁₉N₂NaO₆S
• 分子量: 402.39700
• 闪点: 340.9ºC
• 精确质量: 402.08600
• PSA: 133.30000
• InChIKey: MGFZNWDWOKASQZ-UMLIZJHQSA-M
• SMILES: COc1cccc(OC)c1C(=O)NC1C(=O)N2C1SC(C)(C)C2C(=O)[O-].[Na+]
• 外观性状: white to off-white
• 蒸汽压: 2.94E-17mmHg at 25°C
• 储存条件: 2-8°C
• 水溶解性: Slightly soluble in acetone. Soluble in ethanol or water
• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:1

  3.氢键受体数量:7

  4.可旋转化学键数量:5

  5.互变异构体数量:4

  6.拓扑分子极性表面积133

  7.重原子数量:27

  8.表面电荷:0

  9.复杂度:606

  10.同位素原子数量:0

  11.确定原子立构中心数量:3

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:2

甲氧西林钠毒性和生态

甲氧西林钠安全信息

• 危害码 (欧洲): Xn: Harmful;
• 风险声明 (欧洲): 36/37/38-42/43
• 安全声明 (欧洲): 26-36
• RTECS号: XH8950000

甲氧西林钠靶点实验

查看更多实验

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Lipophilicity was determined 来源：ChEMBL 靶标：N/A External Id：CHEMBL638869

实验名称：ERK5 transcriptional activity HTS 来源：24565 靶标：N/A External Id：ERK5 transcriptional activity-HTS

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School External Id：HMS979

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect... 来源：Broad Institute 靶标：N/A External Id：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

实验名称：Identifying Sarm1 Tir Hydrolase inhibitors through NAD-Glo assay 来源：24386 靶标：N/A External Id：Sarm1 Tir NADase inhibitors screen

实验名称：Increase the activity of the Burkholderia fixLJ 2-component system 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Burkholderia multivorans External Id：HMS1625

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甲氧西林钠英文别名

• (2S,5R,6R)-6-[(2,6-Dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium salt
• Methicillin sodium salt
• Methicillin Sodium
• meticillin sodium
• sodium 6-(2,6-dimethoxybenzamido)penicillanate
• EINECS 205-083-9
• MFCD07787409
• Sodium (2,6-dimethoxyphenyl)penicillin,Sodium methicillin