狗牙花碱 D 乙醚

• 常用名: 狗牙花碱 D 乙醚
• 英文名: Coronarin D ethyl ether
• CAS号: 138965-89-6
• 分子量: 346.504
• 密度: 1.0±0.1 g/cm3
• 沸点: 460.6±45.0 °C at 760 mmHg
• 分子式: C₂₂H₃₄O₃
• 熔点: N/A
• 闪点: 197.8±23.3 °C

狗牙花碱 D 乙醚用途

乙氧冠蛋白D是一种从根茎中分离得到的拉丹二萜化合物。乙氧冠蛋白D选择性抑制COX-1,IC50为3.8µM【1】。

狗牙花碱 D 乙醚名称

• 中文名: 狗牙花碱 D 乙醚
• 英文名: (3E)-5-Ethoxy-3-{2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylenedeca hydro-1-naphthalenyl]ethylidene}dihydro-2(3H)-furanone

狗牙花碱 D 乙醚生物活性

• 描述: 乙氧冠蛋白D是一种从根茎中分离得到的拉丹二萜化合物。乙氧冠蛋白D选择性抑制COX-1,IC50为3.8µM【1】。
• 相关类别:
  研究领域 >> 炎症/免疫
  信号通路 >> 免疫及炎症 >> COX
• 参考文献:

  [1]. Denise C. Endringer, et al. Cancer chemoprevention activity of labdane diterpenes from rhizomes of Hedychium coronarium.

狗牙花碱 D 乙醚物理化学性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 460.6±45.0 °C at 760 mmHg
• 分子式: C₂₂H₃₄O₃
• 分子量: 346.504
• 闪点: 197.8±23.3 °C
• 精确质量: 346.250793
• PSA: 35.53000
• LogP: 6.18
• InChIKey: HUJJMXMBEMUVOX-WOYMVRNGSA-N
• SMILES: C=C1CCC2C(C)(C)CCCC2(C)C1CC=C1CC(OCC)OC1=O
• 外观性状: 油状物体
• 蒸汽压: 0.0±1.1 mmHg at 25°C
• 折射率: 1.515
• 储存条件: 2-8℃，干燥，密闭

狗牙花碱 D 乙醚安全信息

• 危害码 (欧洲): Xi

狗牙花碱 D 乙醚靶点实验

查看更多实验

实验名称：Cytotoxicity against mouse RAW264.7 cells assessed as cell viability at 0.1 uM incuba... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4394976

实验名称：Inhibition of yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4338368

实验名称：Inhibition of yeast alpha-glucosidase at 50 uM using p-nitrophenyl-alpha-D-glucopyran... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4338367

实验名称：Cytotoxicity against mouse RAW264.7 cells assessed as cell viability at 1 uM incubate... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4394978

实验名称：Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4338366

实验名称：Cytotoxicity against mouse RAW264.7 cells assessed as cell viability at 5 uM incubate... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4394979

实验名称：Cytotoxicity against mouse RAW264.7 cells assessed as cell viability at 20 uM incubat... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4394980

实验名称：Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-indu... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4394981

实验名称：Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-indu... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4394982

实验名称：Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-indu... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4394983

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狗牙花碱 D 乙醚英文别名

• coronarin-D ethyl ether
• coronarin B
• (3E)-5-Ethoxy-3-{2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylenedecahydro-1-naphthalenyl]ethylidene}dihydro-2(3H)-furanone