1-脱羧-3-氧代茶酸

• 常用名: 1-脱羧-3-氧代茶酸
• 英文名: 1-Decarboxy-3-oxo-ceathic acid
• CAS号: 214150-74-0
• 分子量: 440.66
• 密度: 1.1±0.1 g/cm3
• 沸点: 535.4±50.0 °C at 760 mmHg
• 分子式: C₂₉H₄₄O₃
• 熔点: N/A
• 闪点: 291.7±26.6 °C

1-脱羧-3-氧代茶酸用途

1-十二烷氧基-3-氧代陶瓷酸是一种抗癌剂。1-十二烷氧基-3-氧代陶瓷酸抑制DNA合成。1-十二烷氧基-3-氧代陶瓷酸诱导细胞凋亡[1]。

1-脱羧-3-氧代茶酸名称

• 中文名: 1-脱羧-3-氧代茶酸
• 英文名: (1R,3aS,5aR,5bR,7aR,10aR,10bR,12aR,12bR)-1-Isopropenyl-5a,5b,8,8, 10a-pentamethyl-9-oxooctadecahydrodicyclopenta[a,i]phenanthrene-3 a(1H)-carboxylic acid

1-脱羧-3-氧代茶酸生物活性

• 描述: 1-十二烷氧基-3-氧代陶瓷酸是一种抗癌剂。1-十二烷氧基-3-氧代陶瓷酸抑制DNA合成。1-十二烷氧基-3-氧代陶瓷酸诱导细胞凋亡[1]。
• 相关类别:
  信号通路 >> 细胞凋亡 >> 细胞凋亡
  研究领域 >> 癌症
  信号通路 >> 细胞周期/DNA损伤 >> DNA/RNA合成
• 参考文献:

  [1]. Su Y, et al. In vitro cytotoxic activity of 1-decarboxy-3-oxo-ceanothic acid in a human ovarian adenocarcinoma cell line. Res Commun Mol Pathol Pharmacol. 1998 Jun;100(3):313-26.

1-脱羧-3-氧代茶酸物理化学性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 535.4±50.0 °C at 760 mmHg
• 分子式: C₂₉H₄₄O₃
• 分子量: 440.66
• 闪点: 291.7±26.6 °C
• 精确质量: 440.329041
• PSA: 54.37000
• LogP: 7.80
• InChIKey: NUDCZUBEFGYVSS-JAEAZDECSA-N
• SMILES: C=C(C)C1CCC2(C(=O)O)CCC3(C)C(CCC4C5(C)CC(=O)C(C)(C)C5CCC43C)C12
• 外观性状: 粉末
• 蒸汽压: 0.0±3.1 mmHg at 25°C
• 折射率: 1.531
• 储存条件: 2-8℃，干燥，密闭

1-脱羧-3-氧代茶酸安全信息

• 危害码 (欧洲): Xi

1-脱羧-3-氧代茶酸靶点实验

查看更多实验

实验名称：Cytotoxicity against human HeLa cells after 48 hrs by MTT assay 来源：ChEMBL 靶标：HeLa External Id：CHEMBL995686

实验名称：Cytotoxicity against human FS5 cells after 48 hrs by MTT assay 来源：ChEMBL 靶标：N/A External Id：CHEMBL995687

实验名称：Cytotoxicity against human OVCAR-3 cells after 48 hrs by MTT assay 来源：ChEMBL 靶标：OVCAR-3 External Id：CHEMBL995685

实验名称：Cytotoxicity against human HeLa cells assessed as cell survival after 48 hrs by MTT a... 来源：ChEMBL 靶标：HeLa External Id：CHEMBL995680

实验名称：Cytotoxicity against human FS5 cells assessed as cell survival after 48 hrs by MTT as... 来源：ChEMBL 靶标：N/A External Id：CHEMBL995681

实验名称：Cytotoxicity against human Raji cells assessed as cell viability at 1000 molar ratio ... 来源：ChEMBL 靶标：Raji External Id：CHEMBL951807

实验名称：Inhibition of TPA-induced EBV-early antigen activation in human Raji cells assessed a... 来源：ChEMBL 靶标：N/A External Id：CHEMBL954656

实验名称：Cytotoxicity against human Raji cells assessed as cell viability at 100 molar ratio a... 来源：ChEMBL 靶标：Raji External Id：CHEMBL951809

实验名称：Cytotoxicity against human Raji cells assessed as cell viability at 500 molar ratio a... 来源：ChEMBL 靶标：Raji External Id：CHEMBL951808

实验名称：Inhibition of TPA-induced EBV-early antigen activation in human Raji cells assessed a... 来源：ChEMBL 靶标：N/A External Id：CHEMBL954653

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1-脱羧-3-氧代茶酸英文别名

• (1R,3aS,5aR,5bR,7aR,10aR,10bR,12aR,12bR)-1-Isopropenyl-5a,5b,8,8,10a-pentamethyl-9-oxooctadecahydrodicyclopenta[a,i]phenanthrene-3a(1H)-carboxylic acid