BCX 1470甲磺酸盐

• 常用名: BCX 1470甲磺酸盐
• 英文名: BCX 1470 (methanesulfonate)
• CAS号: 217099-44-0
• 分子量: 398.47700
• 密度: N/A
• 沸点: 509.9ºC at 760 mmHg
• 分子式: C₁₅H₁₄N₂O₅S₃
• 熔点: N/A
• 闪点: 262.2ºC

BCX 1470甲磺酸盐用途

BCX 1470能抑制factor D和C1s的酯水解活性,IC50分别为96 nM和1.6 nM。

BCX 1470甲磺酸盐名称

• 中文名: 2-(氨基亚氨基甲基)苯并[b]噻吩-6-基 2-噻吩羧酸酯甲磺酸盐 (1:1)
• 英文名: 2-Thiophenecarboxylic acid 2-(aminoiminomethyl)benzo[b]thiophen-6-yl ester methanesulfonate (1:1)
• 中文别名: 2-(氨基亚氨基甲基)苯并[b]噻吩-6-基酯 2-噻吩羧酸甲烷磺酸

BCX 1470甲磺酸盐生物活性

• 描述: BCX 1470能抑制factor D和C1s的酯水解活性,IC50分别为96 nM和1.6 nM。
• 相关类别:
  信号通路 >> 免疫及炎症 >> 补充系统
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Szalai, Alexander J.; Digerness, Stanley B.; et al.; The Arthus Reaction in Rodents: Species-Specific Requirement of ComplementJournal of Immunology, 2000, 164, 463-468

  [2]. Szalai AJ, Digerness SB, Agrawal A, Kearney JF, Bucy RP, Niwas S, Kilpatrick JM, Babu YS, Volanakis JE.The Arthus reaction in rodents: species-specific requirement of complement.J Immunol. 2000 Jan 1;164(1):463-8.

BCX 1470甲磺酸盐物理化学性质

• 沸点: 509.9ºC at 760 mmHg
• 分子式: C₁₅H₁₄N₂O₅S₃
• 分子量: 398.47700
• 闪点: 262.2ºC
• 精确质量: 398.00600
• PSA: 195.40000
• LogP: 4.85090
• InChIKey: MCPAUXMAIOICMC-UHFFFAOYSA-N
• SMILES: CS(=O)(=O)O.N=C(N)c1cc2ccc(OC(=O)c3cccs3)cc2s1
• 储存条件: 2-8℃

BCX 1470甲磺酸盐靶点实验

查看更多实验

实验名称：Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VER... 来源：ChEMBL 靶标：Severe acute respiratory syndrome coronavirus 2 External Id：CHEMBL4513082

实验名称：A screen for small molecules that modulate mitochondrial supercomplex formation 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1482

实验名称：Inhibition of complement system in human fetal serum assessed as inhibition of hemoly... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2209179

实验名称：Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Cac... 来源：ChEMBL 靶标：Severe acute respiratory syndrome coronavirus 2 External Id：CHEMBL4303805

实验名称：SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f... 来源：ChEMBL 靶标：Replicase polyprotein 1ab External Id：CHEMBL4495582

实验名称：Stabilization of p53 in human papillomavirus-positive cells 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Cellular tumor antigen p53 External Id：HMS1485

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BCX 1470甲磺酸盐英文别名

• BCX 1470 methanesulfonate
• BCX 1470 (methanesulfonate)