BTB06584

• 常用名: BTB06584
• 英文名: BTB06584
• CAS号: 219793-45-0
• 分子量: 417.820
• 密度: 1.5±0.1 g/cm3
• 沸点: 664.8±55.0 °C at 760 mmHg
• 分子式: C₁₉H₁₂ClNO₆S
• 熔点: N/A
• 闪点: 355.9±31.5 °C
• 符号: GHS05
• 信号词: Danger

BTB06584用途

BTB06584是一种IF1依赖性的选择性线粒体F1Fo-ATP酶抑制剂。

BTB06584名称

• 中文名: 4-氯-苯甲酸 2-硝基-5-(苯磺酰基)苯基酯
• 英文名: 2-nitro-5-(phenylsulfonyl)phenyl 4-chlorobenzoate

BTB06584生物活性

• 描述: BTB06584是一种IF1依赖性的选择性线粒体F1Fo-ATP酶抑制剂。
• 相关类别:
  信号通路 >> 跨膜转运 >> ATP合成酶
  研究领域 >> 癌症
• 参考文献:

  [1]. Ivanes F, et al. The compound BTB06584 is an IF1 -dependent selective inhibitor of the mitochondrial F1 Fo-ATPase. Br J Pharmacol. 2014 Sep;171(18):4193-4206.

BTB06584物理化学性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 664.8±55.0 °C at 760 mmHg
• 分子式: C₁₉H₁₂ClNO₆S
• 分子量: 417.820
• 闪点: 355.9±31.5 °C
• 精确质量: 417.007385
• PSA: 114.64000
• LogP: 5.23
• InChIKey: WNDWKKPBLAKXMI-UHFFFAOYSA-N
• SMILES: O=C(Oc1cc(S(=O)(=O)c2ccccc2)ccc1[N+](=O)[O-])c1ccc(Cl)cc1
• 外观性状: 粉末
• 蒸汽压: 0.0±2.0 mmHg at 25°C
• 折射率: 1.637
• 储存条件: -20℃

BTB06584安全信息

• 符号: GHS05
• 信号词: Danger
• 危害声明: H318
• 警示性声明: P280-P305 + P351 + P338
• 危险品运输编码: NONH for all modes of transport

BTB06584靶点实验

查看更多实验

实验名称：Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：HCMV UL50 External Id：HMS1262

实验名称：Screen for inhibitors of RMI FANCM (MM2) intereaction 来源：11908 靶标：N/A External Id：RMI-FANCM-MM2

实验名称：Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VER... 来源：ChEMBL 靶标：Severe acute respiratory syndrome coronavirus 2 External Id：CHEMBL4513082

实验名称：Cytotoxicity against rat H9c2 cells assessed as reduction in cell survival at 100 uM ... 来源：ChEMBL 靶标：H9c2 External Id：CHEMBL5392618

实验名称：Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Cac... 来源：ChEMBL 靶标：Severe acute respiratory syndrome coronavirus 2 External Id：CHEMBL4303805

实验名称：SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f... 来源：ChEMBL 靶标：Replicase polyprotein 1ab External Id：CHEMBL4495582

实验名称：Induction of mitochondrial membrane potential loss in rat H9c2 cells assessed as incr... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5392614

实验名称：Stabilization of p53 in human papillomavirus-positive cells 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Cellular tumor antigen p53 External Id：HMS1485

实验名称：Induction of mitochondrial membrane potential loss in rat H9c2 cells assessed as incr... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5392611

实验名称：Enzymatic assay of human HDAC6 with commercial peptide substrate 来源：ChEMBL 靶标：Histone deacetylase 6 External Id：CHEMBL4808149

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BTB06584英文别名

• AHAS inhibitor
• 2-Nitro-5-(phenylsulfonyl)phenyl 4-chlorobenzoate
• Benzoic acid, 4-chloro-, 2-nitro-5-(phenylsulfonyl)phenyl ester
• BTB06584