糠酸二氯尼特

• 常用名: 糠酸二氯尼特
• 英文名: Diloxanide furoate
• CAS号: 3736-81-0
• 分子量: 328.14700
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₄H₁₁Cl₂NO₄
• 熔点: N/A
• 闪点: N/A
• 符号: GHS07
• 信号词: Warning

糠酸二氯尼特用途

Diloxanide furoate是阿米巴病的治疗中使用的腔抗阿米巴药,被认为是治疗轻度肠阿米巴病或无症状囊肿携带者的首选。

糠酸二氯尼特名称

• 中文名: 糠酸二氯尼特
• 英文名: [4-[(2,2-dichloroacetyl)-methylamino]phenyl] furan-2-carboxylate
• 中文别名: 4-(N-甲基-2,2-二氯乙酰氨基)苯基 2-糠酸酯 | 糠酯酰胺

糠酸二氯尼特生物活性

• 描述: Diloxanide furoate是阿米巴病的治疗中使用的腔抗阿米巴药,被认为是治疗轻度肠阿米巴病或无症状囊肿携带者的首选。
• 相关类别:
  信号通路 >> 抗感染 >> 寄生物
  研究领域 >> 感染
• 参考文献:

  [1]. Castro Hermida JA, et al. Inhibition of Cryptosporidium infection in mice treated with a cyclodextrin inclusion complex with diloxanide furoate. Parasitol Res. 2001 Jun;87(6):449-52.

  [2]. Martínez-Castillo M, et al. Flavonoids as a Natural Treatment Against Entamoeba histolytica. Front Cell Infect Microbiol. 2018 Jun 22;8:209.

糠酸二氯尼特物理化学性质

• 分子式: C₁₄H₁₁Cl₂NO₄
• 分子量: 328.14700
• 精确质量: 327.00700
• PSA: 59.75000
• LogP: 3.26530
• InChIKey: BDYYDXJSHYEDGB-UHFFFAOYSA-N
• SMILES: CN(C(=O)C(Cl)Cl)c1ccc(OC(=O)c2ccco2)cc1
• 储存条件: 2-8℃

糠酸二氯尼特毒性和生态

糠酸二氯尼特安全信息

• 符号: GHS07
• 信号词: Warning
• 危害声明: H302
• 个人防护装备: dust mask type N95 (US);Eyeshields;Gloves
• 危害码 (欧洲): Xn
• 风险声明 (欧洲): 22
• 安全声明 (欧洲): 36
• 危险品运输编码: NONH for all modes of transport
• WGK德国: 3
• RTECS号: LV1821800

糠酸二氯尼特靶点实验

查看更多实验

实验名称：Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression 来源：NCGC External Id：SNCA-p-activity-luciferase

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu... 来源：824 External Id：CYP273

实验名称：Increase the activity of the Burkholderia fixLJ 2-component system 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Burkholderia multivorans External Id：HMS1625

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：qHTS for Inhibitors of TGF-b: Cytotox Counterscreen 来源：NCGC 靶标：N/A External Id：SMAD3201

实验名称：uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay 来源：Burnham Center for Chemical Genomics 靶标：cystic fibrosis transmembrane conductance regulator [Homo sapiens] External Id：SBCCG-A764-CF-PAF-Primary-Assay

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ant... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_ANT_FLUO8_1536_1X%INH PRUN

实验名称：qHTS for Inhibitors of TGF-b 来源：NCGC 靶标：Smad3 [Homo sapiens] External Id：SMAD3101

实验名称：Primary qHTS for inhibitors of NSP2Pro chikungunya virus (CHIKV) 来源：NCGC External Id：APP-Toga-CHIKV-nsp2-p

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糠酸二氯尼特英文别名

• Amebiazol
• Miforon
• MFCD00083302
• Diclofurazol
• Diloxanid furoate
• Furamide (amebicide)
• Entamide furoate
• Furentomin
• Entamide 2-furoate
• Histomibal
• DILOXANIDE FUROATE
• EINECS 223-108-1