氯化三己基乙酯

• 常用名: 氯化三己基乙酯
• 英文名: tridihexethyl chloride
• CAS号: 4310-35-4
• 分子量: 353.97000
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₁H₃₆ClNO
• 熔点: N/A
• 闪点: N/A

氯化三己基乙酯用途

氯化三二己乙酯(Pathilon)是一种口服活性抗胆碱能药物和mAChR拮抗剂,具有抗肌萎缩和抗胆碱能活性。三氯二己酯对胃肠道有明显的解痉和抗分泌作用。氯化三己酯可用于研究消化性溃疡病和后天性眼震[1][2]。

氯化三己基乙酯名称

• 中文名: 氯化三己基乙酯
• 英文名: tridihexethyl chloride

氯化三己基乙酯生物活性

• 描述: 氯化三二己乙酯(Pathilon)是一种口服活性抗胆碱能药物和mAChR拮抗剂,具有抗肌萎缩和抗胆碱能活性。三氯二己酯对胃肠道有明显的解痉和抗分泌作用。氯化三己酯可用于研究消化性溃疡病和后天性眼震[1][2]。
• 相关类别:
  信号通路 >> 神经信号通路 >> mAChR
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 由mAChR
  研究领域 >> 炎症/免疫
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Leigh RJ, et al. Effect of anticholinergic agents upon acquired nystagmus: a double-blind study of trihexyphenidyl and tridihexethyl chloride. Neurology. 1991 Nov;41(11):1737-41.

  [2]. Jabbari B, et al. ffectiveness of trihexyphenidyl against pendular nystagmus and palatal myoclonus: evidence of cholinergic dysfunction. Mov Disord. 1987;2(2):93-8.

氯化三己基乙酯物理化学性质

• 分子式: C₂₁H₃₆ClNO
• 分子量: 353.97000
• 精确质量: 353.24900
• PSA: 20.23000
• LogP: 1.72510
• InChIKey: XJGONMZLEDGBRM-UHFFFAOYSA-M
• SMILES: CC[N+](CC)(CC)CCC(O)(c1ccccc1)C1CCCCC1.[Cl-]

氯化三己基乙酯安全信息

• 危险品运输编码: NONH for all modes of transport
• 海关编码: 2923900090

氯化三己基乙酯海关

• 海关编码: 2923900090
• 中文概述: 2923900090 其他季铵盐及季铵碱。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%
• 申报要素: 品名, 成分含量, 用途
• Summary: 2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

氯化三己基乙酯靶点实验

查看更多实验

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Dicer-mediated maturation of pre-microRNA 来源：Center for Chemical Genomics, University of Michigan 靶标：N/A External Id：TargetID_659_CEMA

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：Fluorescence polarization-based biochemical high throughput primary assay to identify... 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens] External Id：SIAE_INH_FP_1536_1X%INH PRUN

实验名称：qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cell fr... 来源：824 靶标：N/A External Id：SPEC167MG

实验名称：qHTS assay to test for compound auto fluorescence at 590 nm (red) in HEK293 cell free... 来源：824 靶标：N/A External Id：SPEC167MR

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氯化三己基乙酯英文别名

• (3-cyclohexyl-3-hydroxy-3-phenylpropyl)-triethylazanium,chloride
• EINECS 224-323-3
• Tridihexethyl chloride
• (3-Cyclohexyl-3-hydroxy-3-phenylpropyl)triethylammonium chloride
• 60-49-1 (Parent)
• Pathilon chloride
• 3-cyclohexyl-N,N,N-triethyl-3-hydroxy-3-phenylpropan-1-aminium chloride
• Tridihexethyl chloride (BAN)