Amitriptylinoxide

• 常用名: Amitriptylinoxide
• 英文名: Amitriptylinoxide
• CAS号: 4317-14-0
• 分子量: 293.40
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₂₃NO
• 熔点: N/A
• 闪点: N/A

Amitriptylinoxide用途

阿米替林氧化物(Equilibrin)是阿米替林的类似物和代谢产物,具有类似的抗抑郁功效[1]。

Amitriptylinoxide名称

• 英文名: amitriptyline N-oxide

Amitriptylinoxide生物活性

• 描述: 阿米替林氧化物(Equilibrin)是阿米替林的类似物和代谢产物,具有类似的抗抑郁功效[1]。
• 相关类别:
  研究领域 >> 神经疾病
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 5-HT受体
  信号通路 >> 神经信号通路 >> 5-HT受体
• 参考文献:

  [1]. J Tegeler, et al. Double-blind study of the therapeutic efficacy and tolerability of amitriptylinoxide in comparison with amitriptyline. Pharmacopsychiatry. 1990 Jan;23(1):45-9.

Amitriptylinoxide物理化学性质

• 分子式: C₂₀H₂₃NO
• 分子量: 293.40
• 精确质量: 293.17800
• PSA: 29.43000
• LogP: 4.20210
• InChIKey: ZPMKQFOGINQDAM-UHFFFAOYSA-N
• SMILES: C[N+](C)([O-])CCC=C1c2ccccc2CCc2ccccc21

Amitriptylinoxide毒性和生态

Amitriptylinoxide靶点实验

查看更多实验

实验名称：Substrate activity at human mARC1 expressed in Escherichia coli assessed as turnover ... 来源：ChEMBL 靶标：Mitochondrial amidoxime-reducing component 1 External Id：CHEMBL4614174

实验名称：Observed volume of distribution 来源：ChEMBL 靶标：N/A External Id：CHEMBL624569

实验名称：Substrate activity at human mARC1 expressed in Escherichia coli assessed as turnover ... 来源：ChEMBL 靶标：Mitochondrial amidoxime-reducing component 1 External Id：CHEMBL4614164

实验名称：Unbound fraction (plasma) 来源：ChEMBL 靶标：N/A External Id：CHEMBL618310

实验名称：Substrate activity at human mARC2 expressed in Escherichia coli assessed as turnover ... 来源：ChEMBL 靶标：Mitochondrial amidoxime reducing component 2 External Id：CHEMBL4614179

实验名称：Dissociation constant (pKa) 来源：ChEMBL 靶标：N/A External Id：CHEMBL635170

实验名称：Substrate activity at human mARC2 expressed in Escherichia coli assessed as turnover ... 来源：ChEMBL 靶标：Mitochondrial amidoxime reducing component 2 External Id：CHEMBL4614169

实验名称：Kinase Assay from US Patent US8629135: "Pharmaceutical compositions comprising RET in... 来源：BindingDB 靶标：N/A External Id：BindingDB_6165_1

实验名称：HIV Cellular Data 来源：NIAID 靶标：N/A External Id：HIV Cellular Data

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Amitriptylinoxide英文别名

• amitriptyline-N-oxide
• amitriptylinoxide
• 5-(3-Dimethylaminopropyliden)dibenzo<a.d>cycloheptan-N-oxid
• Amitriptylinoxide (inn)
• Amitriptylin-N-oxid