雌莫司汀磷酸钠

• 常用名: 雌莫司汀磷酸钠
• 英文名: Estramustine phosphate sodium
• CAS号: 52205-73-9
• 分子量: 564.347
• 密度: 1.253g/cm3
• 沸点: 565.8ºC at 760mmHg
• 分子式: C₂₃H₃₀Cl₂NNa₂O₆P
• 熔点: N/A
• 闪点: 296ºC

雌莫司汀磷酸钠用途

Estramustine磷酸钠盐是抗微管蛋白化疗试剂。

雌莫司汀磷酸钠名称

• 中文名: 雌莫司汀磷酸钠
• 英文名: estramustine sodium phosphate
• 中文别名: 雌莫司丁磷酸钠

雌莫司汀磷酸钠生物活性

• 描述: Estramustine磷酸钠盐是抗微管蛋白化疗试剂。
• 相关类别:
  信号通路 >> 细胞周期/DNA损伤 >> 微管/微管蛋白
  信号通路 >> 细胞骨架 >> 微管/微管蛋白
  研究领域 >> 癌症
• 参考文献:

  [1]. Perry CM, et al. Estramustine phosphate sodium. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in prostate cancer. Drugs Aging. 1995 Jul;7(1):49-74.

  [2]. Bergenheim AT, et al. Pharmacokinetics and pharmacodynamics of estramustine phosphate. Clin Pharmacokinet. 1998 Feb;34(2):163-72.

  [3]. Dene Simpson, et al. Estramustine Phosphate Sodium. American Journal of Cancer 2 (5):373–390.

雌莫司汀磷酸钠物理化学性质

• 密度: 1.253g/cm3
• 沸点: 565.8ºC at 760mmHg
• 分子式: C₂₃H₃₀Cl₂NNa₂O₆P
• 分子量: 564.347
• 闪点: 296ºC
• 精确质量: 563.098328
• PSA: 111.77000
• LogP: 6.17540
• 储存条件: room temp

雌莫司汀磷酸钠毒性和生态

雌莫司汀磷酸钠安全信息

• 个人防护装备: dust mask type N95 (US);Eyeshields;Gloves
• 危害码 (欧洲): Xi
• 风险声明 (欧洲): 37
• 安全声明 (欧洲): 26
• 危险品运输编码: NONH for all modes of transport
• RTECS号: KG7350000

雌莫司汀磷酸钠英文别名

• EINECS 257-735-7
• Estramustine phosphate disodium
• Ro 21-8837/001
• Estramustine sodium phosphate
• iumphosphate
• estracytsodium
• Estracyt
• carbamic acid, bis(2-chloroethyl)-, (17β)-17-(phosphonooxy)estra-1,3,5(10)-trien-3-yl ester, disodium salt
• disodium (8R,9S,13S,14S,17S)-3-{[bis(2-chloroethyl)carbamoyl]oxy}-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-yl phosphate
• Disodium (17β)-3-{[bis(2-chloroethyl)carbamoyl]oxy}estra-1(10),2,4-trien-17-yl phosphate
• Carbamic acid, N,N-bis(2-chloroethyl)-, (17β)-17-(phosphonooxy)estra-1(10),2,4-trien-3-yl ester, sodium salt (1:2)
• MFCD00866320
• estramustinephosphatedisodium
• estramustine phosphate
• emcyt
• Dinatrium-(8R,9S,13S,14S,17S)-3-{[bis(2-chlorethyl)carbamoyl]oxy}-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-ylphosphat
• Estramustine phosphate sodium
• phosphate de (8R,9S,13S,14S,17S)-3-{[bis(2-chloroéthyl)carbamoyl]oxy}-13-méthyl-7,8,9,11,12,13,14,15,16,17-décahydro-6H-cyclopenta[a]phénanthrén-17-yle de disodium
• Estramustine (phosphate sodium)