(E)-Dehydrodiconiferyl alcohol

• 常用名: (E)-Dehydrodiconiferyl alcohol
• 英文名: (E)-Dehydrodiconiferyl alcohol
• CAS号: 528814-97-3
• 分子量: 358.39
• 密度: N/A
• 沸点: 562.0±50.0 °C(Predicted)
• 分子式: C₂₀H₂₂O₆
• 熔点: 140 - 141 °C
• 闪点: N/A

(E)-Dehydrodiconiferyl alcohol用途

(E) -脱氢异烟肼醇表现为良好的hCA IX和hCA XII双重抑制剂[1]。(E)-脱氢异烟肼醇抑制愈合区结缔组织中的NF-κB核转位[2]。

(E)-Dehydrodiconiferyl alcohol名称

• 中文名: 去氢双松柏醇
• 英文名: Dehydrodiconiferyl alcohol

(E)-Dehydrodiconiferyl alcohol生物活性

• 描述: (E) -脱氢异烟肼醇表现为良好的hCA IX和hCA XII双重抑制剂[1]。(E)-脱氢异烟肼醇抑制愈合区结缔组织中的NF-κB核转位[2]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 代谢酶/蛋白酶 >> 碳酸酐酶
• 参考文献:

  [1]. Costa G, et al. In Silico Identification and Biological Evaluation of Antioxidant Food Components Endowed with IX and XII hCA Inhibition. Antioxidants (Basel). 2020;9(9):775. Published 2020 Aug 21.

  [2]. Hu X, et al. Dehydrodiconiferyl alcohol from Silybum marianum (L.) Gaertn accelerates wound healing via inactivating NF-κB pathways in macrophages. J Pharm Pharmacol. 2020;72(2):305-317.

(E)-Dehydrodiconiferyl alcohol物理化学性质

• 沸点: 562.0±50.0 °C(Predicted)
• 熔点: 140 - 141 °C
• 分子式: C₂₀H₂₂O₆
• 分子量: 358.39
• 储存条件: 2-8℃

(E)-Dehydrodiconiferyl alcohol安全信息

• 危害码 (欧洲): Xi

(E)-Dehydrodiconiferyl alcohol靶点实验

查看更多实验

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实验名称：Anti-osteoporotic activity in Balb/c mouse assessed as inhibition of OVX-induced TRAP... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4150179

实验名称：Anti-osteoporotic activity in Balb/c mouse assessed as inhibition of OVX-induced NFAT... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4150180

实验名称：Selectivity ratio of IC50 for recombinant human full length untagged ERbeta expressed... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4150167

实验名称：Anti-osteoporotic activity in ip dosed OVX-induced bone loss in femur of Balb/c mouse... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4150168

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实验名称：Inhibition of RANKL-induced osteoclast differentiation in mouse RAW264.7 cells harbor... 来源：ChEMBL 靶标：RAW264.7 External Id：CHEMBL4150162

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