泰妙菌素

• 常用名: 泰妙菌素
• 英文名: Tiamulin
• CAS号: 55297-95-5
• 分子量: 493.742
• 密度: 1.1±0.1 g/cm3
• 沸点: 563.0±50.0 °C at 760 mmHg
• 分子式: C₂₈H₄₇NO₄S
• 熔点: 147-148ºC
• 闪点: 294.3±30.1 °C

泰妙菌素用途

Tiamulin fumarate (Thiamutilin fumarate) 是一类二萜兽药,广泛用于控制猪的传染疾病,包括猪痢疾和地方性肺炎等。

泰妙菌素名称

• 中文名: 硫姆林
• 英文名: tiamulin
• 中文别名: 泰妙菌素

泰妙菌素生物活性

• 描述: Tiamulin fumarate (Thiamutilin fumarate) 是一类二萜兽药,广泛用于控制猪的传染疾病,包括猪痢疾和地方性肺炎等。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 参考文献:

  [1]. Noa M, et al. Tiamulin-nitrovin interaction in pigs: a case report and experimental reproduction. Vet Hum Toxicol. 2000 Oct;42(5):286-8.

  [2]. Dreyfuss J, et al. Metabolism of tritium- and carbon-14-labeled tiamulin in dogs, rats, and pigs. J Antibiot (Tokyo). 1979 May;32(5):496-503.

  [3]. Islam KM, et al. The activity and compatibility of the antibiotic tiamulin with other drugs in poultry medicine--A review. Poult Sci. 2009 Nov;88(11):2353-9.

泰妙菌素物理化学性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 563.0±50.0 °C at 760 mmHg
• 熔点: 147-148ºC
• 分子式: C₂₈H₄₇NO₄S
• 分子量: 493.742
• 闪点: 294.3±30.1 °C
• 精确质量: 493.322571
• PSA: 92.14000
• LogP: 5.93
• InChIKey: UURAUHCOJAIIRQ-UHFFFAOYSA-N
• SMILES: C=CC1(C)CC(OC(=O)CSCCN(CC)CC)C2(C)C(C)CCC3(CCC(=O)C32)C(C)C1O
• 蒸汽压: 0.0±3.5 mmHg at 25°C
• 折射率: 1.541
• 储存条件: 2-8°C

泰妙菌素安全信息

• 危害声明: H413
• 个人防护装备: Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
• 危害码 (欧洲): Xn
• 危险品运输编码: NONH for all modes of transport
• RTECS号: AG9552000

泰妙菌素靶点实验

查看更多实验

实验名称：Antibacterial activity against pleuromutilin-resistant Enterococcus faecium 18SC29-2 ... 来源：ChEMBL 靶标：Enterococcus faecium External Id：CHEMBL5615744

实验名称：Antibacterial activity against pleuromutilin-resistant Enterococcus faecium 18FJZ1-1 ... 来源：ChEMBL 靶标：Enterococcus faecium External Id：CHEMBL5615745

实验名称：Antibacterial activity against methicillin-resistant Staphylococcus aureus J1 harbori... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL5615746

实验名称：Antibacterial activity against pleuromutilin-resistant Staphylococcus simulans isolat... 来源：ChEMBL 靶标：Staphylococcus simulans External Id：CHEMBL5615747

实验名称：TP_TRANSPORTER: increase in Daunomycin intracellular accumulation (Daunomycin: 1.9 uM... 来源：ChEMBL 靶标：ATP-dependent translocase ABCB1 External Id：CHEMBL2077387

实验名称：Antibacterial activity against clinical-derived Staphylococcus aureus isolate 42262 b... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL1691858

实验名称：Antimicrobial activity against methicillin-resistant Escherichia coli AS19 after 20 h... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL3119550

实验名称：Antibacterial activity against clinical-derived Staphylococcus aureus isolate harbori... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL1691859

实验名称：Antimicrobial activity against methicillin-resistant Staphylococcus aureus RN4220 aft... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL3119551

实验名称：Antibacterial activity against clinical-derived Staphylococcus aureus isolate 51312 h... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL1692007

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泰妙菌素英文别名

• Tiamulin
• EINECS 259-580-0
• MFCD01672098
• thiamutilin
• TiaMulin fuMerate API
• 14-Desoxy-14-[(2-diethylaminoethyl)mercaptoacetoxy]mutilin
• (1S,2R,3S,4S,6R,7R,8R,14R)-3-Hydroxy-2,4,7,14-tetramethyl-9-oxo-4-vinyltricyclo[5.4.3.0]tetradec-6-yl {[2-(diethylamino)ethyl]sulfanyl}acetate
• tiavetp
• Tiamutin
• Acetic acid, 2-[[2-(diethylamino)ethyl]thio]-, (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester
• TIAMILIN