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头孢美唑钠

更新时间:2025-08-20 16:37:11

头孢美唑钠结构式
头孢美唑钠结构式
品牌特惠专场
常用名 头孢美唑钠 英文名 Cefmetazole Sodium
CAS号 56796-39-5 分子量 493.516
密度 1.75 g/cm3 沸点 N/A
分子式 C15H16N7NaO5S3 熔点 N/A
MSDS 中文版 美版 闪点 N/A
符号 GHS07 GHS08
GHS07, GHS08
信号词 Danger

 头孢美唑钠用途


Cefmetazole钠是一种半合成的广谱头孢菌素类抗菌剂。

 头孢美唑钠名称

中文名 头孢美唑钠
英文名 cefmetazole sodium
中文别名 (6R,7S)-7-[[2-(氰甲基硫)乙酰]氨基]-7-甲氧基-3-[(1-甲基四唑-5-基)硫甲基]-8-氧代-5-硫杂-1-氮杂双环[4.2.0]辛-2-烯-2-甲酸钠盐
英文别名 更多

 头孢美唑钠生物活性

描述 Cefmetazole钠是一种半合成的广谱头孢菌素类抗菌剂。
相关类别
参考文献

[1]. Schentag JJ, et al. Cefmetazole sodium: pharmacology, pharmacokinetics, and clinical trials. Pharmacotherapy. 1991;11(1):2-19.

 头孢美唑钠物理化学性质

密度 1.75 g/cm3
分子式 C15H16N7NaO5S3
分子量 493.516
精确质量 493.027283
PSA 242.06000
InChIKey BITQGIOJQWZUPL-PBCQUBLHSA-M
SMILES COC1(NC(=O)CSCC#N)C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC21.[Na+]
外观性状 白色固体
储存条件 库房低温通风干燥
水溶解性 水溶性:完全溶解;易溶于:甲醇;可溶于:丙酮;极微溶:乙醇;不溶:氯仿,四氢呋喃

 头孢美唑钠毒性和生态

 头孢美唑钠安全信息

符号 GHS07 GHS08
GHS07, GHS08
信号词 Danger
危害声明 H315-H317-H319-H334-H335
警示性声明 P261-P280-P305 + P351 + P338-P342 + P311
危害码 (欧洲) Xi:Irritant;
风险声明 (欧洲) R36/37/38;R42/43
安全声明 (欧洲) S26-S36
危险品运输编码 NONH for all modes of transport
WGK德国 2
RTECS号 XI0372200

 头孢美唑钠文献29

更多文献
Chimeric mice with humanized liver.

Toxicology 246(1) , 9-17, (2008)

Recently, chimeric mice with humanized liver were established by transplanting human hepatocytes into an urokinase-type plasminogen activator(+/+)/severe combined immunodeficient transgenic mouse line...

Usefulness of sennoside as an agent for mechanical bowel preparation prior to elective colon cancer surgery

Asian J. Surg. 35(2) , 81-7, (2012)

Objective We retrospectively evaluated the usefulness of sennoside as an agent for mechanical bowel preparation prior to elective colon cancer surgery.

Involvement of multidrug resistance-associated protein 4 in efflux transport of prostaglandin E(2) across mouse blood-brain barrier and its inhibition by intravenous administration of cephalosporins.

J. Pharmacol. Exp. Ther. 333 , 912-919, (2010)

Prostaglandin E(2) (PGE(2)) acts as a modulator of synaptic signaling and excitability in the brain. Because PGE(2) is barely inactivated enzymatically in adult brain, its brain level is considered to...

 头孢美唑钠靶点实验

查看更多实验

实验名称:Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay
来源:ChEMBL
靶标:N/A
External Id:CHEMBL1266185
实验名称:Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
来源:NCGC
External Id:SNCA-p-activity-luciferase
实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_AG_FLUO8_1536_1X%ACT PRUN
实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify pos...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
实验名称:qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity
来源:NCGC
External Id:HERG01
实验名称:qHTS for Inhibitors of TGF-b: Cytotox Counterscreen
来源:NCGC
靶标:N/A
External Id:SMAD3201
实验名称:uHTS identification of cystic fibrosis induced NFkb Inhibitors in a fluoresence assay
来源:Burnham Center for Chemical Genomics
靶标:cystic fibrosis transmembrane conductance regulator [Homo sapiens]
External Id:SBCCG-A764-CF-PAF-Primary-Assay
实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify ant...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_ANT_FLUO8_1536_1X%INH PRUN
实验名称:qHTS for Inhibitors of TGF-b
来源:NCGC
靶标:Smad3 [Homo sapiens]
External Id:SMAD3101
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 头孢美唑钠英文别名

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[2-[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, sodium salt, (6R,7S)- (1:1)
sodium,(6R,7S)-7-[[2-(cyanomethylsulfanyl)acetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Sodium (6R,7S)-7-(2-((Cyanomethyl)thio)acetamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
MFCD00865068
Cefmetazole Sodium Salt
Sodium (6R,7S)-7-({[(cyanomethyl)sulfanyl]acetyl}amino)-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Cefmetazole (sodium)
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