Piperlonguminine

• 常用名: Piperlonguminine
• 英文名: Piperlonguminine
• CAS号: 5950-12-9
• 分子量: 273.327
• 密度: 1.1±0.1 g/cm3
• 沸点: 476.9±45.0 °C at 760 mmHg
• 分子式: C₁₆H₁₉NO₃
• 熔点: N/A
• 闪点: 242.2±28.7 °C

Piperlonguminine用途

Piperlonguminine 是一种从 Piper 中分离出的生物碱酰胺。Piperlonguminine 具有多种生物学特性,包括抗炎,抗肿瘤,神经保护,抗血小板,抗黑素生成,抗真菌和抗菌活性。

Piperlonguminine名称

• 中文名: 荜茇宁
• 英文名: Piperlonguminine

Piperlonguminine生物活性

• 描述: Piperlonguminine 是一种从 Piper 中分离出的生物碱酰胺。Piperlonguminine 具有多种生物学特性,包括抗炎,抗肿瘤,神经保护,抗血小板,抗黑素生成,抗真菌和抗菌活性。
• 相关类别:
  研究领域 >> 癌症
  研究领域 >> 心血管疾病
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 真菌
  研究领域 >> 炎症/免疫
  研究领域 >> 神经疾病
  信号通路 >> 抗感染 >> 细菌
• 参考文献:

  [1]. Bezerra DP, et, al. In vivo growth inhibition of sarcoma 180 by piperlonguminine, an alkaloid amide from the Piper species. J Appl Toxicol. 2008 Jul; 28(5): 599-607.

  [2]. Yang T, et, al. Piperlonguminine is neuroprotective in experimental rat stroke. Int Immunopharmacol. 2014 Dec; 23(2): 447-51.

  [3]. Marques JV, et, al. Antifungal amides from Piper scutifolium and Piper hoffmanseggianum. J Nat Prod. 2007 Dec; 70(12):2036-9.

  [4]. Chy MNU, et, al. Antibacterial, anthelmintic, and analgesic activities of Piper sylvaticum (Roxb.) leaves and in silico molecular docking and PASS prediction studies of its isolated compounds. J Complement Integr Med. 2019 Aug 22;16(4).

Piperlonguminine物理化学性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 476.9±45.0 °C at 760 mmHg
• 分子式: C₁₆H₁₉NO₃
• 分子量: 273.327
• 闪点: 242.2±28.7 °C
• 精确质量: 273.136505
• PSA: 47.56000
• LogP: 2.78
• InChIKey: WHAAPCGHVWVUEX-GGWOSOGESA-N
• SMILES: CC(C)CNC(=O)C=CC=Cc1ccc2c(c1)OCO2
• 外观性状: 粉末
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.577
• 储存条件: 2-8℃

Piperlonguminine安全信息

• 海关编码: 2932999099

Piperlonguminine海关

• 海关编码: 2932999099
• 中文概述: 2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途
• Summary: 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Piperlonguminine靶点实验

查看更多实验

实验名称：Activation of rat GABA alpha-1-beta-2-gamma-2 receptor expressed in xenopus oocytes a... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1102660

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect... 来源：Broad Institute 靶标：N/A External Id：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

实验名称：Activation of rat GABA alpha-1-beta-2-gamma-2 receptor expressed in xenopus oocytes a... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1102663

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify pos... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_PAM_FLUO8_1536_1X%ACT PRUN

实验名称：Fluorescence polarization-based biochemical high throughput primary assay to identify... 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens] External Id：SIAE_INH_FP_1536_1X%INH PRUN

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Piperlonguminine英文别名

• Piperlonguminine
• (2E,4E)-5-(3,4-methylenedioxyphenyl)-2,4-pentadienoic acid N-isobutylamide
• (2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)-N-isobutylpenta-2,4-dienamide
• (2E,4E)-5-(1,3-benzodioxol-5-yl)-N-(2-methylpropyl)penta-2,4-dienamide
• (E,E)-Piperlonguminine
• piperlongumine
• (2E,4E)-5-(1,3-benzodioxol-5-yl)-N-(2-methylpropyl)-2,4-pentadienamide
• 5-benzo[1,3]dioxol-5-yl-N-(2-methylpropyl)penta-2,4-dienamide
• (2E,4E)-5-(1,3-Benzodioxol-5-yl)-N-isobutyl-2,4-pentadienamide
• 5-(3',4'-methylenedioxy-phenyl)-2E,4E-pentadienoic acid isobutyl amide
• mexedrone