巴西红

• 常用名: 巴西红
• 英文名: Brazilein
• CAS号: 600-76-0
• 分子量: 284.26300
• 密度: 1.65g/cm3
• 沸点: 683.8ºC at 760 mmHg
• 分子式: C₁₆H₁₂O₅
• 熔点: N/A
• 闪点: 264.9ºC

巴西红用途

Brazilein是从苏木中分离出的一种重要的免疫抑制成分。Brazilein诱导小鼠脾淋巴细胞凋亡[1]。

巴西红名称

• 中文名: 巴西红
• 英文名: 6a,9,10-trihydroxy-6,7-dihydroindeno[2,1-c]chromen-3-one

巴西红生物活性

• 描述: Brazilein是从苏木中分离出的一种重要的免疫抑制成分。Brazilein诱导小鼠脾淋巴细胞凋亡[1]。
• 相关类别:
  信号通路 >> 细胞凋亡 >> 细胞凋亡
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Ye M, et al. Brazilein, an important immunosuppressive component from Caesalpinia sappan L. Int Immunopharmacol. 2006;6(3):426-432.

巴西红物理化学性质

• 密度: 1.65g/cm3
• 沸点: 683.8ºC at 760 mmHg
• 分子式: C₁₆H₁₂O₅
• 分子量: 284.26300
• 闪点: 264.9ºC
• 精确质量: 284.06800
• PSA: 86.99000
• LogP: 1.19160
• InChIKey: PGERTGWKXFAEFR-UHFFFAOYSA-N
• SMILES: O=C1C=CC2=C3c4cc(O)c(O)cc4CC3(O)COC2=C1
• 折射率: 1.784

巴西红靶点实验

查看更多实验

实验名称：Antiinflammatory activity in human neutrophils assessed as inhibition of fMLP/cytocha... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL1064992

实验名称：Antiinflammatory activity in human neutrophils assessed as inhibition of fMLP/cytocha... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL1064990

实验名称：Cytotoxicity against human Hep3B cells after 3 days by MTT assay 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL1920633

实验名称：Cytotoxicity against human Ca9-22 cells after 3 days by MTT assay 来源：ChEMBL 靶标：Ca9-22 External Id：CHEMBL1920632

实验名称：Cytotoxicity against human HepG2 cells after 3 days by MTT assay 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL1920634

实验名称：Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimo... 来源：ChEMBL 靶标：Solute carrier organic anion transporter family member 1B3 External Id：CHEMBL3039491

实验名称：Human Phosphogluconate dehydrogenase (6PGD) Inhibitor Screening 来源：11827 靶标：Phosphogluconate dehydrogenase External Id：6PGD_Inhibitor_Screening_2015_09

实验名称：Antiestrogenic activity in human ER-positive MCF7 cells assessed as inhibition of 17b... 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL1920625

实验名称：Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimo... 来源：ChEMBL 靶标：Solute carrier organic anion transporter family member 1B1 External Id：CHEMBL3039488

实验名称：Estrogenic activity in transgenic Arabidopsis thaliana transfected with pER8:GUS plas... 来源：ChEMBL 靶标：Arabidopsis thaliana External Id：CHEMBL1920627

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巴西红英文别名

• MLWIYODOURBGPI-UHFFFAOYSA
• 3,6A,10-trihydroxy-6a,7-dihydro-6H-indeno[2,1-c]chromen-9-one
• Benz(b)indeno(1,2-d)pyran-9(6H)-one,6a,7-dihydro-3,6a,10-trihydroxy
• 3,6A,10-trihydroxy-6a,7-dihydro-6H-indeno[2,1-c]chromen-9-on
• 6a,7-dihydro-3,6a,10-trihydroxybenz[b]indeno[1,2-d]pyran-9(6H)-one
• Brazilein