Brazilein

Modify Date: 2024-01-20 19:24:35

Brazilein Structure
Brazilein structure
Common Name Brazilein
CAS Number 600-76-0 Molecular Weight 284.26300
Density 1.65g/cm3 Boiling Point 683.8ºC at 760 mmHg
Molecular Formula C16H12O5 Melting Point N/A
MSDS N/A Flash Point 264.9ºC

 Use of Brazilein


Brazilein is an important immunosuppressive component isolated from Caesalpinia sappan L. Brazilein induces apoptosis in mice spleen lymphocytes[1].

 Names

Name 6a,9,10-trihydroxy-6,7-dihydroindeno[2,1-c]chromen-3-one
Synonym More Synonyms

 Brazilein Biological Activity

Description Brazilein is an important immunosuppressive component isolated from Caesalpinia sappan L. Brazilein induces apoptosis in mice spleen lymphocytes[1].
Related Catalog
References

[1]. Ye M, et al. Brazilein, an important immunosuppressive component from Caesalpinia sappan L. Int Immunopharmacol. 2006;6(3):426-432.

 Chemical & Physical Properties

Density 1.65g/cm3
Boiling Point 683.8ºC at 760 mmHg
Molecular Formula C16H12O5
Molecular Weight 284.26300
Flash Point 264.9ºC
Exact Mass 284.06800
PSA 86.99000
LogP 1.19160
Index of Refraction 1.784

 Synthetic Route

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Brazilein Structure

Brazilein

CAS#:600-76-0

Literature: Liebermann; Burg Chemische Berichte, 1876 , vol. 9, p. 1886 Full Text Show Details Benedikt Justus Liebigs Annalen der Chemie, 1875 , vol. 178, p. 101 Anm.

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Brazilein Structure

Brazilein

CAS#:600-76-0

Literature: Schall Chemische Berichte, 1902 , vol. 35, p. 2306 Full Text Show Details Schall; Dralle Chemische Berichte, 1890 , vol. 23, p. 1433

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Detail
Literature: Buchka; Erck Chemische Berichte, 1885 , vol. 18, p. 1139 Full Text Show Details Reim Chemische Berichte, 1871 , vol. 4, p. 334

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Brazilein Structure

Brazilein

CAS#:600-76-0

Literature: Yen, Chiao-Ting; Nakagawa-Goto, Kyoko; Hwang, Tsong-Long; Wu, Pei-Chi; Morris-Natschke, Susan L.; Lai, Wan-Chun; Bastow, Kenneth F.; Chang, Fang-Rong; Wu, Yang-Chang; Lee, Kuo-Hsiung Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 3 p. 1037 - 1039

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Detail
Literature: Liebermann; Burg Chemische Berichte, 1876 , vol. 9, p. 1886 Full Text Show Details Engels; Perkin,W. H.; Robinson Journal of the Chemical Society, 1908 , vol. 93, p. 1131

 Synonyms

MLWIYODOURBGPI-UHFFFAOYSA
3,6A,10-trihydroxy-6a,7-dihydro-6H-indeno[2,1-c]chromen-9-one
Benz(b)indeno(1,2-d)pyran-9(6H)-one,6a,7-dihydro-3,6a,10-trihydroxy
3,6A,10-trihydroxy-6a,7-dihydro-6H-indeno[2,1-c]chromen-9-on
6a,7-dihydro-3,6a,10-trihydroxybenz[b]indeno[1,2-d]pyran-9(6H)-one
Brazilein