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2,3,5,6,7,8-六氢-1H-环戊并[b]喹啉-9-胺

更新时间:2025-08-25 19:07:25

2,3,5,6,7,8-六氢-1H-环戊并[b]喹啉-9-胺结构式
2,3,5,6,7,8-六氢-1H-环戊并[b]喹啉-9-胺结构式
品牌特惠专场
常用名 2,3,5,6,7,8-六氢-1H-环戊并[b]喹啉-9-胺 英文名 Ipidacrine
CAS号 62732-44-9 分子量 188.26900
密度 1.17 g/cm3 沸点 367.969ºC at 760 mmHg
分子式 C12H16N2 熔点 N/A
MSDS N/A 闪点 203.991ºC

 2,3,5,6,7,8-六氢-1H-环戊并[b]喹啉-9-胺用途


2,3,5,6,7,8-六氢-1H-环戊烷[b]喹啉-9-胺是一种药物活性化合物,是一种促智剂,用作胆碱酯酶抑制剂,用于治疗阿尔茨海默病[1]。

 2,3,5,6,7,8-六氢-1H-环戊并[b]喹啉-9-胺名称

中文名 2,3,5,6,7,8-六氢-1H-环戊并[b]喹啉-9-胺
英文名 2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine
英文别名 更多

 2,3,5,6,7,8-六氢-1H-环戊并[b]喹啉-9-胺生物活性

描述 2,3,5,6,7,8-六氢-1H-环戊烷[b]喹啉-9-胺是一种药物活性化合物,是一种促智剂,用作胆碱酯酶抑制剂,用于治疗阿尔茨海默病[1]。
相关类别
参考文献

[1]. A.Dubika, K. Veldre, et al. Phase Transitions of Ipidacrine Hydrochloride Polymorphs and Hydrates. The Open Conference Proceedings Journal, 2011, 2, 21-27.

 2,3,5,6,7,8-六氢-1H-环戊并[b]喹啉-9-胺物理化学性质

密度 1.17 g/cm3
沸点 367.969ºC at 760 mmHg
分子式 C12H16N2
分子量 188.26900
闪点 203.991ºC
精确质量 188.13100
PSA 38.91000
LogP 2.61250
InChIKey YLUSMKAJIQOXPV-UHFFFAOYSA-N
SMILES Nc1c2c(nc3c1CCC3)CCCC2
折射率 1.634
储存条件 2-8°C,密封,干燥

 2,3,5,6,7,8-六氢-1H-环戊并[b]喹啉-9-胺毒性和生态

 2,3,5,6,7,8-六氢-1H-环戊并[b]喹啉-9-胺安全信息

危害码 (欧洲) Xi

 2,3,5,6,7,8-六氢-1H-环戊并[b]喹啉-9-胺合成线路

~76%

2,3,5,6,7,8-六氢-1H-环戊并[b]喹啉-9-胺结构式

2,3,5,6,7,8-六氢-...

62732-44-9

文献:Upadysheva, A. V.; Grigor'eva, N. D.; Ryabokobylko, Yu. S.; Znamenskaya, A. P. Chemistry of Heterocyclic Compounds (New York, NY, United States), 1983 , p. 95 - 99 Khimiya Geterotsiklicheskikh Soedinenii, 1983 , vol. 19, # 1 p. 107 - 111

~%

2,3,5,6,7,8-六氢-1H-环戊并[b]喹啉-9-胺结构式

2,3,5,6,7,8-六氢-...

62732-44-9

文献:Pharmaceutical Chemistry Journal, , vol. 26, # 9-10 p. 769 - 772 Khimiko-Farmatsevticheskii Zhurnal, , vol. 26, # 9-10 p. 83 - 85

 2,3,5,6,7,8-六氢-1H-环戊并[b]喹啉-9-胺上下游产品

2,3,5,6,7,8-六氢-1H-环戊并[b]喹啉-9-胺上游产品  3

2,3,5,6,7,8-六氢-1H-环戊并[b]喹啉-9-胺下游产品  0

 2,3,5,6,7,8-六氢-1H-环戊并[b]喹啉-9-胺靶点实验

查看更多实验

实验名称:Primary cell-based high-throughput screening assay for identification of compounds th...
来源:Johns Hopkins Ion Channel Center
靶标:regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id:JHICC_RGS_Act_HTS
实验名称:qHTS Assay for Inhibitors of the Phosphatase Activity of Eya2
来源:NCGC
靶标:eyes absent homolog 2 isoform a [Homo sapiens]
External Id:EYA2477
实验名称:Compound was evaluated for its acid dissociation constant
来源:ChEMBL
靶标:N/A
External Id:CHEMBL634809
实验名称:uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
来源:Burnham Center for Chemical Genomics
靶标:N/A
External Id:BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
实验名称:Antibacterial activity against Staphylococcus aureus MRSA ATCC 43300 (CO-ADD:GP_020);...
来源:ChEMBL
靶标:Staphylococcus aureus
External Id:CHEMBL4296184
实验名称:Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit...
来源:ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
靶标:N/A
External Id:HMS1315
实验名称:Antibacterial activity against Klebsiella pneumoniae MDR ATCC 70063 (CO-ADD:GN_003); ...
来源:ChEMBL
靶标:Klebsiella pneumoniae
External Id:CHEMBL4296186
实验名称:Primary cell-based high-throughput screening for identification of compounds that all...
来源:Johns Hopkins Ion Channel Center
靶标:MAS-related GPR member X1 [Homo sapiens]
External Id:JHICC_MrgX1_AlloAgonist_Primary
实验名称:Antibacterial activity against Escherichia coli ATCC 25922 (CO-ADD:GN_001); MIC in CA...
来源:ChEMBL
靶标:Escherichia coli
External Id:CHEMBL4296185
实验名称:A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
来源:ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id:HMS979
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 2,3,5,6,7,8-六氢-1H-环戊并[b]喹啉-9-胺英文别名

Amiridine
Ipidacrine
9-amino-2,3,5,6,7,8-hexahydro-1-cyclopenta<b>quinoline
Amiridin
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