2,3,5,6,7,8-六氢-1H-环戊并[b]喹啉-9-胺结构式
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常用名 | 2,3,5,6,7,8-六氢-1H-环戊并[b]喹啉-9-胺 | 英文名 | Ipidacrine |
|---|---|---|---|---|
| CAS号 | 62732-44-9 | 分子量 | 188.26900 | |
| 密度 | 1.17 g/cm3 | 沸点 | 367.969ºC at 760 mmHg | |
| 分子式 | C12H16N2 | 熔点 | N/A | |
| MSDS | N/A | 闪点 | 203.991ºC |
2,3,5,6,7,8-六氢-1H-环戊并[b]喹啉-9-胺用途2,3,5,6,7,8-六氢-1H-环戊烷[b]喹啉-9-胺是一种药物活性化合物,是一种促智剂,用作胆碱酯酶抑制剂,用于治疗阿尔茨海默病[1]。 |
| 中文名 | 2,3,5,6,7,8-六氢-1H-环戊并[b]喹啉-9-胺 |
|---|---|
| 英文名 | 2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine |
| 英文别名 | 更多 |
| 密度 | 1.17 g/cm3 |
|---|---|
| 沸点 | 367.969ºC at 760 mmHg |
| 分子式 | C12H16N2 |
| 分子量 | 188.26900 |
| 闪点 | 203.991ºC |
| 精确质量 | 188.13100 |
| PSA | 38.91000 |
| LogP | 2.61250 |
| InChIKey | YLUSMKAJIQOXPV-UHFFFAOYSA-N |
| SMILES | Nc1c2c(nc3c1CCC3)CCCC2 |
| 折射率 | 1.634 |
| 储存条件 | 2-8°C,密封,干燥 |
| 危害码 (欧洲) | Xi |
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~76%
2,3,5,6,7,8-六氢-... 62732-44-9 |
| 文献:Upadysheva, A. V.; Grigor'eva, N. D.; Ryabokobylko, Yu. S.; Znamenskaya, A. P. Chemistry of Heterocyclic Compounds (New York, NY, United States), 1983 , p. 95 - 99 Khimiya Geterotsiklicheskikh Soedinenii, 1983 , vol. 19, # 1 p. 107 - 111 |
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~%
2,3,5,6,7,8-六氢-... 62732-44-9 |
| 文献:Pharmaceutical Chemistry Journal, , vol. 26, # 9-10 p. 769 - 772 Khimiko-Farmatsevticheskii Zhurnal, , vol. 26, # 9-10 p. 83 - 85 |
| 2,3,5,6,7,8-六氢-1H-环戊并[b]喹啉-9-胺上游产品 3 | |
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| 2,3,5,6,7,8-六氢-1H-环戊并[b]喹啉-9-胺下游产品 0 | |
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实验名称:Primary cell-based high-throughput screening assay for identification of compounds th...
来源:Johns Hopkins Ion Channel Center
靶标:regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id:JHICC_RGS_Act_HTS
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实验名称:qHTS Assay for Inhibitors of the Phosphatase Activity of Eya2
来源:NCGC
靶标:eyes absent homolog 2 isoform a [Homo sapiens]
External Id:EYA2477
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实验名称:Compound was evaluated for its acid dissociation constant
来源:ChEMBL
靶标:N/A
External Id:CHEMBL634809
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实验名称:uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
来源:Burnham Center for Chemical Genomics
靶标:N/A
External Id:BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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实验名称:Antibacterial activity against Staphylococcus aureus MRSA ATCC 43300 (CO-ADD:GP_020);...
来源:ChEMBL
靶标:Staphylococcus aureus
External Id:CHEMBL4296184
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实验名称:Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit...
来源:ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
靶标:N/A
External Id:HMS1315
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实验名称:Antibacterial activity against Klebsiella pneumoniae MDR ATCC 70063 (CO-ADD:GN_003); ...
来源:ChEMBL
靶标:Klebsiella pneumoniae
External Id:CHEMBL4296186
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实验名称:Primary cell-based high-throughput screening for identification of compounds that all...
来源:Johns Hopkins Ion Channel Center
靶标:MAS-related GPR member X1 [Homo sapiens]
External Id:JHICC_MrgX1_AlloAgonist_Primary
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实验名称:Antibacterial activity against Escherichia coli ATCC 25922 (CO-ADD:GN_001); MIC in CA...
来源:ChEMBL
靶标:Escherichia coli
External Id:CHEMBL4296185
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实验名称:A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
来源:ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id:HMS979
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| Amiridine |
| Ipidacrine |
| 9-amino-2,3,5,6,7,8-hexahydro-1-cyclopenta<b>quinoline |
| Amiridin |