二氢白屈菜红碱

• 常用名: 二氢白屈菜红碱
• 英文名: Dihydrochelerythrine
• CAS号: 6880-91-7
• 分子量: 349.380
• 密度: 1.3±0.1 g/cm3
• 沸点: 565.9±50.0 °C at 760 mmHg
• 分子式: C₂₁H₁₉NO₄
• 熔点: N/A
• 闪点: 171.6±27.3 °C

二氢白屈菜红碱用途

二氢白屈菜红碱(Dihydrochelerythrine)是从榕树叶片分离出的天然化合物,具抗真菌等活性。

二氢白屈菜红碱名称

• 中文名: 二氢白屈菜红碱
• 英文名: 1,2-dimethoxy-12-methyl-13H-[1,3]benzodioxolo[5,6-c]phenanthridine

二氢白屈菜红碱生物活性

• 描述: 二氢白屈菜红碱(Dihydrochelerythrine)是从榕树叶片分离出的天然化合物,具抗真菌等活性。
• 相关类别:
  信号通路 >> 抗感染 >> 真菌
  天然产物 >> 生物碱
  研究领域 >> 感染
• 参考文献:

  [1]. Feng G, et al. Inhibitory activity of dihydrosanguinarine and dihydrochelerythrine against phytopathogenic fungi. Nat Prod Res. 2011 Jul;25(11):1082-9.

  [2]. Vrba J, et al. Chelerythrine and dihydrochelerythrine induce G1 phase arrest and bimodal cell death in human leukemia HL-60 cells. Toxicol In Vitro. 2008 Jun;22(4):1008-17.

  [3]. Tantapakul C, et al. Antibacterial compounds from Zanthoxylum rhetsa. Arch Pharm Res. 2012 Jul;35(7):1139-42.

二氢白屈菜红碱物理化学性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 565.9±50.0 °C at 760 mmHg
• 分子式: C₂₁H₁₉NO₄
• 分子量: 349.380
• 闪点: 171.6±27.3 °C
• 精确质量: 349.131409
• PSA: 40.16000
• LogP: 4.56
• InChIKey: ALZAZMCIBRHMFF-UHFFFAOYSA-N
• SMILES: COc1ccc2c(c1OC)CN(C)c1c-2ccc2cc3c(cc12)OCO3
• 蒸汽压: 0.0±1.5 mmHg at 25°C
• 折射率: 1.657
• 储存条件: 2-8℃

二氢白屈菜红碱安全信息

• 海关编码: 2933990090

二氢白屈菜红碱海关

• 海关编码: 2933990090
• 中文概述: 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
• Summary: 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

二氢白屈菜红碱靶点实验

查看更多实验

实验名称：Experimentally measured binding affinity data (Kd) for protein-ligand complexes deriv... 来源：Shanghai Institute of Organic Chemistry 靶标：N/A External Id：PDBbind-Kd for protein-ligand complexes

实验名称：Experimentally measured binding affinity data (IC50) for protein-ligand complexes der... 来源：Shanghai Institute of Organic Chemistry 靶标：N/A External Id：PDBbind-IC50 for protein-ligand complexes

实验名称：Antimicrobial activity against Penicillium oxalicum CBS 219.30 at 25 ug 来源：ChEMBL 靶标：Penicillium oxalicum External Id：CHEMBL1019284

实验名称：Antimicrobial activity against Micrococcus luteus ATCC 9341 at 25 ug 来源：ChEMBL 靶标：Micrococcus luteus External Id：CHEMBL1019286

实验名称：Antimicrobial activity against Bacillus subtilis ATCC 6633 at 25 ug 来源：ChEMBL 靶标：Bacillus subtilis External Id：CHEMBL1019285

实验名称：Binding affinity to duplex DNA (unknown origin) assessed as change in melting tempera... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3811044

实验名称：Binding affinity to c-Kit1 G-quadruplex DNA (unknown origin) assessed as change in me... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3811043

实验名称：Binding affinity to c-myc G-quadruplex DNA (unknown origin) assessed as change in mel... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3811042

实验名称：Time dependent inhibition of CYP3A4 (unknown origin) at 50 uM measured after 5 to 15 ... 来源：ChEMBL 靶标：Cytochrome P450 3A4 External Id：CHEMBL5530150

实验名称：Antiproliferative activity against human HeLa cells at 0.1 to 20 uM after 72 hrs by M... 来源：ChEMBL 靶标：HeLa External Id：CHEMBL3811049

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二氢白屈菜红碱英文别名

• bocconoline
• Dihydrochelerythrine
• 5,6-dihydrochelerythrine
• 12,13-dihydrochelerythrine
• 1,2-Dimethoxy-12-methyl-12,13-dihydro[1,3]benzodioxolo[5,6-c]phenanthridine