夫西地酸

• 常用名: 夫西地酸
• 英文名: fusidic acid
• CAS号: 6990-06-3
• 分子量: 516.709
• 密度: 1.2±0.1 g/cm3
• 沸点: 635.6±55.0 °C at 760 mmHg
• 分子式: C₃₁H₄₈O₆
• 熔点: 190-192ºC
• 闪点: 197.7±25.0 °C
• 符号: GHS07
• 信号词: Warning

夫西地酸用途

Fusidic acid (Fusidate) 是一种抑菌抗生素。

夫西地酸名称

• 中文名: 夫西地酸
• 英文名: fusidic acid
• 中文别名: 褐霉酸

夫西地酸生物活性

• 描述: Fusidic acid (Fusidate) 是一种抑菌抗生素。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 靶点实验:

  Bacterial[1][2][3]

• 参考文献:

  [1]. Falagas ME, et al. Potential of old-generation antibiotics to address current need for new antibiotics. Expert Rev Anti Infect Ther. 2008 Oct;6(5):593-600.

  [2]. Leclercq R, et al. In vitro activity of fusidic acid against streptococci isolated from skin and soft tissue infections. J Antimicrob Chemother. 2000 Jan;45(1):27-9.

  [3]. Spelman D, et al. Fusidic acid in skin and soft tissue infections. Int J Antimicrob Agents. 1999 Aug;12 Suppl 2:S59-66.

夫西地酸物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 635.6±55.0 °C at 760 mmHg
• 熔点: 190-192ºC
• 分子式: C₃₁H₄₈O₆
• 分子量: 516.709
• 闪点: 197.7±25.0 °C
• 精确质量: 516.345093
• PSA: 104.06000
• LogP: 6.41
• InChIKey: IECPWNUMDGFDKC-MZJAQBGESA-N
• SMILES: CC(=O)OC1CC2(C)C(CC(O)C3C4(C)CCC(O)C(C)C4CCC32C)C1=C(CCC=C(C)C)C(=O)O
• 外观性状: 白色固体
• 蒸汽压: 0.0±4.2 mmHg at 25°C
• 折射率: 1.558
• 储存条件: 2-8°C
• 水溶解性: 水溶性：实际上不溶；可溶于：氯仿,醇,丙酮,二噁烷；极微溶：乙醚

夫西地酸毒性和生态

夫西地酸安全信息

• 符号: GHS07
• 信号词: Warning
• 危害声明: H302
• 警示性声明: P301 + P312 + P330
• 个人防护装备: dust mask type N95 (US);Eyeshields;Gloves
• 危害码 (欧洲): Xn
• 风险声明 (欧洲): R22
• 安全声明 (欧洲): 36
• 危险品运输编码: NONH for all modes of transport
• RTECS号: RC1350000
• 海关编码: 2942000000

夫西地酸海关

• 海关编码: 2942000000

夫西地酸靶点实验

查看更多实验

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：Antibacterial activity against Acinetobacter baumannii ATCC 19606 by Etest method in ... 来源：ChEMBL 靶标：Acinetobacter baumannii External Id：CHEMBL1680550

实验名称：Antibacterial activity against Acinetobacter baumannii ATCC 19606 by Etest method in ... 来源：ChEMBL 靶标：Acinetobacter baumannii External Id：CHEMBL1680551

实验名称：Antibacterial activity against Acinetobacter baumannii ATCC 19606 by Etest method in ... 来源：ChEMBL 靶标：Acinetobacter baumannii External Id：CHEMBL1680552

实验名称：Antibacterial activity against Acinetobacter baumannii ATCC 19606 by Etest method in ... 来源：ChEMBL 靶标：Acinetobacter baumannii External Id：CHEMBL1680553

实验名称：Antibacterial activity against Acinetobacter baumannii ATCC 19606 by Etest method in ... 来源：ChEMBL 靶标：Acinetobacter baumannii External Id：CHEMBL1680554

实验名称：Antibacterial activity against Acinetobacter baumannii ATCC 19606 by Etest method 来源：ChEMBL 靶标：Acinetobacter baumannii External Id：CHEMBL1680555

实验名称：Antibacterial activity against revertant Staphylococcus aureus at pH 7.4 after 24 hrs... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL1696170

实验名称：Antibacterial activity against normal phenotype Staphylococcus aureus at pH 7.4 after... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL1696171

实验名称：Cmax in human plasma 来源：ChEMBL 靶标：Plasma External Id：CHEMBL1696172

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夫西地酸英文别名

• (2Z)-2-[(3α,4α,5α,8α,9β,11α,13α,14β,16β,17Z)-16-(acetyloxy)-3,11-dihydroxy-4,8,10,14-tetramethylgonan-17-ylidene]-6-methylhept-5-enoic acid
• Fucidic acid
• Fusidate sodium
• EINECS 230-256-0
• fusidic acid
• Fusidin
• FUCIDIN
• (2Z)-2-[(3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetyloxy-3,11-dihydroxy-4,8,10,14-tetramethyl-2,3,4,5,6,7,9,11,12,13,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ylidene]-6-methylhept-5-enoic acid
• (2Z)-2-[(3α,4α,5α,8α,9β,11α,13α,14β,16β,17Z)-16-Acetoxy-3,11-dihydroxy-4,8,10,14-tetramethylgonan-17-ylidene]-6-methylhept-5-enoic acid
• Fusidate
• Ramycin
• fusdic acid
• (3α,4α,5α,8α,9β,11α,13α,14β,16β,17Z)-16-Acetoxy-3,11-dihydroxy-4,8,14-trimethyl-18-norcholesta-17,24-dien-21-oic acid
• Fucithalmic
• Fucidin acid
• MFCD00865135
• 3,11,16-Trihydroxy-4,8,10,14-tetramethyl-17-(1'-carboxyisohept-4'-enylidene)cyclopentanoperhydrophenanthrene 16-Acetate
• FusidicAcid
• (3a,4a,8a,9b,11a,13a,14b,16b,17Z)-16-(Acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic Acid
• Diethanolamine fusidate
• Fusidine