SKF-82958氢溴酸盐

• 常用名: SKF-82958氢溴酸盐
• 英文名: SKF 82958 hydrobromide
• CAS号: 74115-01-8
• 分子量: 410.73300
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₉H₂₁BrClNO₂
• 熔点: N/A
• 闪点: N/A

SKF-82958氢溴酸盐用途

SKF 82958盐酸盐是多巴胺D1/D5受体激动剂。

SKF-82958氢溴酸盐名称

• 中文名: SKF-82958氢溴酸盐
• 英文名: 3-allyl-6-chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide

SKF-82958氢溴酸盐生物活性

• 描述: SKF 82958盐酸盐是多巴胺D1/D5受体激动剂。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 多巴胺受体
  信号通路 >> 神经信号通路 >> 多巴胺受体
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Wang JQ, et al. The Full D1 Dopamine Receptor Agonist SKF-82958 Induces Neuropeptide mRNA in the Normosensitive Striatum of Rats: Regulation of D1/D2 Interactions by Muscarinic Receptors.J Pharmacol Exp Ther. 1997 May;281(2):972-82.

SKF-82958氢溴酸盐物理化学性质

• 分子式: C₁₉H₂₁BrClNO₂
• 分子量: 410.73300
• 精确质量: 409.04400
• PSA: 43.70000
• LogP: 4.82320
• InChIKey: WLXGFAVTAAQOFH-UHFFFAOYSA-N
• SMILES: Br.C=CCN1CCc2c(cc(O)c(O)c2Cl)C(c2ccccc2)C1
• 储存条件: 2-8℃

SKF-82958氢溴酸盐靶点实验

查看更多实验

实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：qHTS to identify inhibitors of the New Delhi Metallo-beta-lactamase (NDM): assay vali... 来源：NCGC External Id：adst_MBL_Abs_LOPAC_o1

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Inhibition of neurosphere proliferation of mouse neural precursor cells by MTT assay 来源：ChEMBL 靶标：N/A External Id：CHEMBL1266185

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：Central dopaminergic activity for minimum concentration which produced 500 rotations(... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL794227

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：High throughput fluorescence intensity-based biochemical assay to screen for small mo... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens] External Id：MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

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SKF-82958氢溴酸盐英文别名

• 6-chloro-N-allyl-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-[1H]-3-benzazepine hydrobromide
• (+/-)-6-chloro-7,8-dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide
• (±)-chloro-APB hydrobromide
• chloro-APB hydrobromide
• (±)-SKF-82958 hydrobromide
• SKF 82958 hydrobromide
• 3-Allyl-6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol
• hydrobromide
• SKF-82958 (hydrobromide)