黄柏酮

更新时间：2025-08-24 10:42:19

黄柏酮结构式	常用名	黄柏酮	英文名	Obacunone
	CAS号	751-03-1	分子量	454.512
	密度	1.3±0.1 g/cm3	沸点	626.2±55.0 °C at 760 mmHg
	分子式	C₂₆H₃₀O₇	熔点	N/A
	MSDS	中文版美版	闪点	332.5±31.5 °C

黄柏酮用途

Obacunone是从沼泽白葡萄柚种子中分离得到的,通过诱导凋亡发挥抗癌作用。

中文名	黄柏酮
英文名	Obacunone
中文别名	奥巴叩酮
英文别名	更多

描述	Obacunone是从沼泽白葡萄柚种子中分离得到的,通过诱导凋亡发挥抗癌作用。
相关类别	信号通路 >> 细胞凋亡 >> 细胞凋亡研究领域 >> 癌症
参考文献	[1]. Chidambara Murthy KN, et al. Obacunone and obacunone glucoside inhibit human colon cancer (SW480) cells by the induction of apoptosis. Food Chem Toxicol. 2011 Jul;49(7):1616-25.

密度	1.3±0.1 g/cm3
沸点	626.2±55.0 °C at 760 mmHg
分子式	C₂₆H₃₀O₇
分子量	454.512
闪点	332.5±31.5 °C
精确质量	454.199158
PSA	95.34000
LogP	2.91
外观性状	白色粉末
蒸汽压	0.0±1.8 mmHg at 25°C
折射率	1.592
储存条件	2~8℃

危害码 (欧洲)	Xi
安全声明 (欧洲)	24/25
危险品运输编码	NONH for all modes of transport
RTECS号	RR1104200

[Simultaneous determination of jatrorrhizine, palmatine, berberine, and obacunone in Phellodendri Amurensis Cortex by RP-HPLC].

Zhongguo Zhong Yao Za Zhi 35(16) , 2061-4, (2010)

To develop a HPLC method to determine the content of jatrorrhizine, palmatine, berberine, and obacunone in Phellodendri Amurensis Cortex simultaneously. MEHTOD: The separations were carried out at 25 ...

Chemopreventive effect of a mixture of Chinese Herbs (antitumor B) on chemically induced oral carcinogenesis.

Mol. Carcinog. 52(1) , 49-56, (2013)

In this study, we evaluated chemopreventive efficacy of Antitumor B, a Chinese herbal mixture of six plants (Sophora tonkinensis, Polygonum bistorta, Prunella vulgaris, Sonchus arvensis L., Dictamnus ...

Citrus limonoids obacunone and limonin inhibit azoxymethane-induced colon carcinogenesis in rats.

Biofactors 13(1-4) , 213-8, (2000)

Obacunone and limonin are bitter limonoids in citrus. Their modifying effects on the development of aberrant crypt foci (ACF), the activity of detoxification enzymes, glutathione S-transferase (GST) a...

(5aR,5bR,7aS,8S,10aS,11aR,11bR,13aR)-8-(3-Furyl)-1,1,5a,7a,11b-pentamethyl-5b,6,7,7a,8,11b,13,13a-octahydrooxireno[4,4a]isochromeno[6,5-g][2]benzoxepine-3,10,12(1H,5aH,10aH)-trione

OBACUNON

Tricoccin S3

(5aR,5bR,7aS,8R,10aS,11aR,11bR,13aR)-8-(furan-3-yl)-1,1,5a,7a,11b-pentamethyl-5b,6,7,7a,8,11b,13,13a-octahydrooxireno[4,4a]isochromeno[6,5-g][2]benzoxepine-3,10,12(1H,5aH,10aH)-trione

Obacune

Oxireno[4',5']pyrano[4',3':5,6]naphth[2,1-c]oxepin-3,10,12(1H,5aH,10aH)-trione, 8-(3-furanyl)-5b,6,7,7a,8,11b,13,13a-octahydro-1,1,5a,7a,11b-pentamethyl-, (5aR,5bR,7aS,8S,10aS,11aR,11bR,13aR)-

CasiMirolide