Nelumol A

• 常用名: Nelumol A
• 英文名: nelumol a
• CAS号: 77836-86-3
• 分子量: 346.46
• 密度: 1.0±0.1 g/cm3
• 沸点: 500.5±50.0 °C at 760 mmHg
• 分子式: C₂₁H₃₀O₄
• 熔点: N/A
• 闪点: 256.5±30.1 °C

Nelumol A用途

奈鲁莫A是一种法尼糖样X受体(FXR)激动剂[1]。

Nelumol A名称

• 中文名: (2E)-3-[4-[[(2E)-3,7-二甲基-2,6-辛二烯-1-基]氧基]-3,5-二甲氧基苯基]-2-丙烯-1-醇
• 英文名: (E)-3-[4-[(2E)-3,7-dimethylocta-2,6-dienoxy]-3,5-dimethoxyphenyl]prop-2-en-1-ol

Nelumol A生物活性

• 描述: 奈鲁莫A是一种法尼糖样X受体(FXR)激动剂[1]。
• 相关类别:
  信号通路 >> 代谢酶/蛋白酶 >> FXR
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Francesco Epifano, et al. Nelumal A, the active principle from Ligularia nelumbifolia, is a novel farnesoid X receptor agonist. Bioorg Med Chem Lett. 2012 May 1;22(9):3130-5.

Nelumol A物理化学性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 500.5±50.0 °C at 760 mmHg
• 分子式: C₂₁H₃₀O₄
• 分子量: 346.46
• 闪点: 256.5±30.1 °C
• 精确质量: 346.214417
• PSA: 47.92000
• LogP: 5.20
• InChIKey: MWNIFFJAKKQUJF-NRHDHWSESA-N
• SMILES: COc1cc(C=CCO)cc(OC)c1OCC=C(C)CCC=C(C)C
• 外观性状: 粉末
• 蒸汽压: 0.0±1.3 mmHg at 25°C
• 折射率: 1.540
• 储存条件: 2-8℃，干燥，密闭

Nelumol A安全信息

• 危害码 (欧洲): Xi

Nelumol A靶点实验

查看更多实验

实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：Agonist activity at human farnesoid X receptor expressed in human HepG2 cells at 25 u... 来源：ChEMBL 靶标：Bile acid receptor External Id：CHEMBL2025898

实验名称：Agonist activity at human farnesoid X receptor expressed in human HepG2 cells at 50 u... 来源：ChEMBL 靶标：Bile acid receptor External Id：CHEMBL2025899

实验名称：Agonist activity at human farnesoid X receptor expressed in human HepG2 cells at 5 uM... 来源：ChEMBL 靶标：Bile acid receptor External Id：CHEMBL2025896

实验名称：Agonist activity at human farnesoid X receptor expressed in human HepG2 cells at 10 u... 来源：ChEMBL 靶标：Bile acid receptor External Id：CHEMBL2025897

实验名称：High throughput fluorescence intensity-based biochemical assay to screen for small mo... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens] External Id：MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

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Nelumol A英文别名

• O-Geranylsinapyl alcohol
• (2E)-3-(4-{[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]oxy}-3,5-dimethoxyphenyl)-2-propen-1-ol
• (E,E)-3-(4-((3,7-Dimethyl-2,6-octadienyl)oxy)-3,5-dimethoxyphenyl)-2-propen-1-ol
• Nelumol A
• 4-O-geranyl-sinapyl alcohol
• geranyloxy sinapyl alcohol