头孢噻呋

• 常用名: 头孢噻呋
• 英文名: ceftiofur
• CAS号: 80370-57-6
• 分子量: 523.563
• 密度: 1.8±0.1 g/cm3
• 沸点: N/A
• 分子式: C₁₉H₁₇N₅O₇S₃
• 熔点: N/A
• 闪点: N/A

头孢噻呋用途

Ceftiofur 是一种半合成抗生素,对针对家畜的各种革兰氏阳性和革兰氏阴性菌、好氧菌和厌氧菌均有抗菌活性。

头孢噻呋名称

• 中文名: 头孢噻呋
• 英文名: Ceftiofur
• 中文别名: (6R,7R)-7-[2-(2-氨基噻唑-4-基)(甲氧基亚胺基)乙酰胺基]-3-[(2-呋喃基羰基)硫甲基]-8-氧代-5-硫杂-1-氮杂双环[4.2.0]辛-2-烯-2-甲酸 | 头孢替呋钠

头孢噻呋生物活性

• 描述: Ceftiofur 是一种半合成抗生素,对针对家畜的各种革兰氏阳性和革兰氏阴性菌、好氧菌和厌氧菌均有抗菌活性。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 参考文献:

  [1]. Fernández-Varón E, et al. Pharmacokinetics (PK), pharmacodynamics (PD), and PK-PD integration of ceftiofur after a single intravenous, subcutaneous and subcutaneous-LA administration in lactating goats. BMC Vet Res. 2016 Oct 13;12(1):232.

头孢噻呋物理化学性质

• 密度: 1.8±0.1 g/cm3
• 分子式: C₁₉H₁₇N₅O₇S₃
• 分子量: 523.563
• 精确质量: 523.028992
• PSA: 256.26000
• LogP: 2.05
• InChIKey: ZBHXIWJRIFEVQY-UHFFFAOYSA-N
• SMILES: CON=C(C(=O)NC1C(=O)N2C(C(=O)O)=C(CSC(=O)c3ccco3)CSC12)c1csc(N)n1
• 外观性状: 白色至灰白色粉末
• 折射率: 1.820
• 储存条件: 0-6°C

头孢噻呋安全信息

• 个人防护装备: Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
• 安全声明 (欧洲): 24/25
• 危险品运输编码: NONH for all modes of transport
• 海关编码: 2941905700

头孢噻呋海关

• 海关编码: 2941905700

头孢噻呋靶点实验

查看更多实验

实验名称：Antimicrobial activity against Klebsiella pneumoniae D10 expressing aac(6')-Ib-cr, qn... 来源：ChEMBL 靶标：Klebsiella pneumoniae External Id：CHEMBL1633265

实验名称：Antibacterial activity against cefoxitin-resistant Escherichia coli by microdilution ... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL1665861

实验名称：Antimicrobial activity against Klebsiella pneumoniae D24 expressing aac(6')-Ib-cr and... 来源：ChEMBL 靶标：Klebsiella pneumoniae External Id：CHEMBL1633267

实验名称：Antimicrobial activity against Citrobacter freundii D26 expressing qnrB6 and CTX-M-9G... 来源：ChEMBL 靶标：Citrobacter freundii External Id：CHEMBL1633272

实验名称：qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cell fr... 来源：824 靶标：N/A External Id：SPEC167MG

实验名称：qHTS assay to test for compound auto fluorescence at 590 nm (red) in HEK293 cell free... 来源：824 靶标：N/A External Id：SPEC167MR

实验名称：Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 3 (E... 来源：NCGC External Id：epac1-activator-v

实验名称：qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cells 来源：824 靶标：N/A External Id：SPEC167CG

实验名称：Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 3... 来源：NCGC External Id：epac1-inhibitor-v

实验名称：qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HEK293 cell fre... 来源：824 靶标：N/A External Id：SPEC167MB

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头孢噻呋英文别名

• naxcel
• Ceftiofur
• ceftiofur acid
• CEFTIFURHCL
• CeftiofurFreeAcid
• Excenel
• (6R,7R)-7-{[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-[(2-furoylsulfanyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(furan-2-ylcarbonyl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-7-[2-(2-Amino-4-thiazolyl)glyoxylamido]-3-(mercaptomethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid 72-(Z)-(O-Methyloxime)2-Furoate (Ester)
• CM 31-916
• CEFTIOFUR HCL
• [6R-[6a,7b(Z)]]-7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(2-furanylcarbonyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid