Cis-N-阿魏酰酪胺

• 常用名: Cis-N-阿魏酰酪胺
• 英文名: Cis-N-Feruloyltyramine
• CAS号: 80510-09-4
• 分子量: 313.35
• 密度: 1.2±0.1 g/cm3
• 沸点: 554.2±60.0 °C at 760 mmHg
• 分子式: C₁₈H₁₉NO₄
• 熔点: 128-132℃ (chloroform methanol )
• 闪点: 289.0±32.9 °C

Cis-N-阿魏酰酪胺用途

N-cis-Feruloyl tyramine (cis-N-(4-Hydroxypheneth) ferulamide) 是一种天然酚类化合物,对 RAW 264.7 细胞中 LPS 激活的 NO 产生 (NO production) 具有适度的抑制活性。

Cis-N-阿魏酰酪胺名称

• 中文名: 顺式-N-阿魏酰酪胺
• 英文名: (Z)-3-(4-hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]prop-2-enamide

Cis-N-阿魏酰酪胺生物活性

• 描述: N-cis-Feruloyl tyramine (cis-N-(4-Hydroxypheneth) ferulamide) 是一种天然酚类化合物,对 RAW 264.7 细胞中 LPS 激活的 NO 产生 (NO production) 具有适度的抑制活性。
• 相关类别:
  信号通路 >> 免疫及炎症 >> 一氧化氮合酶
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Youngleem Kim, et al. Inhibitory phenolic amides on lipopolysaccharide-induced nitric oxide production in RAW 264.7 cells from Beta vulgaris var. cicla seeds. Phytother Res. 2003 Sep;17(8):983-5.

Cis-N-阿魏酰酪胺物理化学性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 554.2±60.0 °C at 760 mmHg
• 熔点: 128-132℃ (chloroform methanol )
• 分子式: C₁₈H₁₉NO₄
• 分子量: 313.35
• 闪点: 289.0±32.9 °C
• 精确质量: 313.131409
• PSA: 78.79000
• LogP: 3.33
• InChIKey: NPNNKDMSXVRADT-UITAMQMPSA-N
• SMILES: COc1cc(C=CC(=O)NCCc2ccc(O)cc2)ccc1O
• 外观性状: 粉末
• 蒸汽压: 0.0±1.6 mmHg at 25°C
• 折射率: 1.566
• 储存条件: 2-8℃，干燥，密闭

Cis-N-阿魏酰酪胺安全信息

• 危害码 (欧洲): Xi

Cis-N-阿魏酰酪胺靶点实验

查看更多实验

实验名称：Cytotoxicity against human A549 cells by SRB assay 来源：ChEMBL 靶标：A549 External Id：CHEMBL2091938

实验名称：Cytotoxicity against human SKOV3 cells by SRB assay 来源：ChEMBL 靶标：SK-OV-3 External Id：CHEMBL2091939

实验名称：Antineuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-... 来源：ChEMBL 靶标：BV-2 External Id：CHEMBL4835534

实验名称：Cytotoxicity against mouse BV2 cells assessed as reduction in cell viability at 1 to ... 来源：ChEMBL 靶标：BV-2 External Id：CHEMBL4835533

实验名称：Cytotoxicity against mouse BV2 cells assessed as cell viability at 20 uM by MTT assay 来源：ChEMBL 靶标：BV-2 External Id：CHEMBL2091937

实验名称：Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO... 来源：ChEMBL 靶标：BV-2 External Id：CHEMBL2091942

实验名称：Cytotoxicity against human SK-MEL-2 cells by SRB assay 来源：ChEMBL 靶标：SK-MEL-2 External Id：CHEMBL2091940

实验名称：Cytotoxicity against human HCT15 cells by SRB assay 来源：ChEMBL 靶标：HCT-15 External Id：CHEMBL2091941

实验名称：Inhibition of porcine pancreatic lipase using para-nitrophenyl butyrate as substrate ... 来源：ChEMBL 靶标：Pancreatic triacylglycerol lipase External Id：CHEMBL2394359

实验名称：Antiobesity activity in mouse 3T3L1 cells assessed as reduction of fat accumulation a... 来源：ChEMBL 靶标：3T3-L1 External Id：CHEMBL2394358

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Cis-N-阿魏酰酪胺英文别名

• (2E)-3-(4-Hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]acrylamide
• N-cis-feruloyltyramide
• (1E,2E)-3-(4-Hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]-2-propenimidic acid
• cis-N-Feruloyltyramine
• N-Cis-Feruloyl Tyramine