细胞色素P450还原酶

更新时间:2024-02-28 17:01:58

细胞色素P450还原酶结构式
细胞色素P450还原酶结构式
品牌特惠专场
常用名 细胞色素P450还原酶 英文名 cytochrome p450 reductase
CAS号 9039-06-9 分子量 N/A
密度 N/A 沸点 N/A
分子式 N/A 熔点 N/A
MSDS 美版 闪点 N/A

 细胞色素P450还原酶用途


这种酶催化电子转移到细胞色素 P450。该系统在药物和外源性物质的解毒、致癌物质的激活以及内源性底物(如类固醇)的代谢中起主要角色。

 细胞色素P450还原酶名称

中文名 Native Rabbit Cytochrome P450 Reductase induced with phenobarbital
英文名 cytochrome p450 reductase
英文别名 更多

 细胞色素P450还原酶生物活性

描述 Cytochrome P450 reductase 是一种 NADPH-细胞色素还原酶。Cytochrome P450 reductase 在促进芳香酶构象最适合底物结合方面发挥作用。
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参考文献

[1]. Chao Zhang, et al. Effector role of cytochrome P450 reductase for androstenedione binding to human aromatase. Int J Biol Macromol. 2020 Dec 1:164:510-517.  

 细胞色素P450还原酶物理化学性质

储存条件 20°C

 细胞色素P450还原酶安全信息

危害码 (欧洲) C
危险品运输编码 NONH for all modes of transport

 细胞色素P450还原酶文献54

更多文献
The central role of mosquito cytochrome P450 CYP6Zs in insecticide detoxification revealed by functional expression and structural modelling.

Biochem. J. 455(1) , 75-85, (2013)

The resistance of mosquitoes to chemical insecticides is threatening vector control programmes worldwide. Cytochrome P450 monooxygenases (CYPs) are known to play a major role in insecticide resistance...

The role of renal proximal tubule P450 enzymes in chloroform-induced nephrotoxicity: utility of renal specific P450 reductase knockout mouse models.

Toxicol. Appl. Pharmacol. 272(1) , 230-7, (2013)

The kidney is a primary target for numerous toxic compounds. Cytochrome P450 enzymes (P450) are responsible for the metabolic activation of various chemical compounds, and in the kidney are predominan...

Production of human cytochrome P450 2D6 drug metabolites with recombinant microbes--a comparative study.

Biotechnol. J. 7(11) , 1346-58, (2012)

The processes of drug development require efficient strategies to produce the respective drug metabolites, which are often difficult to obtain. Biotransformations employing recombinant microorganisms ...

 细胞色素P450还原酶英文别名

MFCD01093329