cis-trismethoxy Resveratrol

• 常用名: cis-trismethoxy Resveratrol
• 英文名: 3,4',5-trimethoxystilbene
• CAS号: 94608-23-8
• 分子量: 270.323
• 密度: 1.1±0.1 g/cm3
• 沸点: 423.8±35.0 °C at 760 mmHg
• 分子式: C₁₇H₁₈O₃
• 熔点: N/A
• 闪点: 144.4±23.2 °C

cis-trismethoxy Resveratrol用途

顺式三甲氧基白藜芦醇是一种有效的抗有丝分裂试剂。顺式三甲氧基白藜芦醇抑制微管蛋白聚合,IC50值为4μM[1]。

cis-trismethoxy Resveratrol名称

• 中文名: 顺式白藜芦醇三甲醚
• 英文名: cis-trismethoxy Resveratrol

cis-trismethoxy Resveratrol生物活性

• 描述: 顺式三甲氧基白藜芦醇是一种有效的抗有丝分裂试剂。顺式三甲氧基白藜芦醇抑制微管蛋白聚合,IC50值为4μM[1]。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 细胞周期/DNA损伤 >> 微管/微管蛋白
  信号通路 >> 细胞骨架 >> 微管/微管蛋白
• 参考文献:

  [1]. Schneider Y, et al. Resveratrol analog (Z)-3,5,4'-trimethoxystilbene is a potent anti-mitotic drug inhibiting tubulin polymerization. Int J Cancer. 2003 Nov 1;107(2):189-96.

cis-trismethoxy Resveratrol物理化学性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 423.8±35.0 °C at 760 mmHg
• 分子式: C₁₇H₁₈O₃
• 分子量: 270.323
• 闪点: 144.4±23.2 °C
• 精确质量: 270.125580
• PSA: 27.69000
• LogP: 4.61
• InChIKey: GDHNBPHYVRHYCC-PLNGDYQASA-N
• SMILES: COc1ccc(C=Cc2cc(OC)cc(OC)c2)cc1
• 蒸汽压: 0.0±1.0 mmHg at 25°C
• 折射率: 1.600
• 储存条件: -20°C，密闭，干燥

cis-trismethoxy Resveratrol安全信息

• 危害码 (欧洲): Xi
• 风险声明 (欧洲): 41
• 安全声明 (欧洲): 26-39

cis-trismethoxy Resveratrol靶点实验

查看更多实验

实验名称：Cytotoxicity against human Caco2 cells assessed as cell growth inhibition at 0.3 uM b... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3873712

实验名称：Drug level in SCID mouse serum at 10 mg/kg, ip by GC-MS analysis 来源：ChEMBL 靶标：Serum External Id：CHEMBL1248453

实验名称：Minimum inhibitory concentration (MIC) that inhibits all visible growth of the Crypto... 来源：ChEMBL 靶标：Cryptococcus neoformans External Id：CHEMBL664828

实验名称：Compound was evaluated for cytotoxicity against human SKMEL-5 melanoma cell line. 来源：ChEMBL 靶标：SK-MEL-5 External Id：CHEMBL822666

实验名称：Growth inhibition of human DU145 cells after 48 hrs by sulforhodamine B assay 来源：ChEMBL 靶标：DU-145 External Id：CHEMBL1105822

实验名称：Growth inhibition of human NCI-H460 cells after 48 hrs by sulforhodamine B assay 来源：ChEMBL 靶标：NCI-H460 External Id：CHEMBL1105820

实验名称：Growth inhibition of human SF268 cells after 48 hrs by sulforhodamine B assay 来源：ChEMBL 靶标：SF-268 External Id：CHEMBL1105819

实验名称：Inhibition of tubulin polymerization in Homo sapiens (human) solid tumor cells 来源：ChEMBL 靶标：Tubulin alpha-3C chain External Id：CHEMBL3075002

实验名称：Growth inhibition of human BxPC3 cells after 48 hrs by sulforhodamine B assay 来源：ChEMBL 靶标：BXPC-3 External Id：CHEMBL1105817

实验名称：Cytotoxicity against human Caco-2 cells after 3 days by [3H]thymidine incorporation a... 来源：ChEMBL 靶标：Caco-2 External Id：CHEMBL1248459

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cis-trismethoxy Resveratrol英文别名

• 1,3-Dimethoxy-5-[(Z)-2-(4-methoxyphenyl)vinyl]benzene
• 3,5,4'-Trimethoxystilbene
• 1,3-dimethoxy-5-[(E)-2-(4-methoxyphenyl)ethenyl]benzene
• 1,3-dimethoxy-5-[(Z)-2-(4-methoxyphenyl)ethenyl]benzene
• 3,4',5-trimethoxystilbene
• cis-4-methoxy-3',5'-dimethoxystilbene
• 1,3-Dimethoxy-5-[(E)-2-(4-methoxyphenyl)vinyl]benzene
• 1,3-Dimethoxy-5-[(E)-2-(4-methoxy-phenyl)-vinyl]-benzene