4-(N-BOC-AMINO)PIPERIDINE structure
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Common Name | 4-(N-BOC-AMINO)PIPERIDINE | ||
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CAS Number | 73874-95-0 | Molecular Weight | 200.28 | |
Density | 1.0±0.1 g/cm3 | Boiling Point | 304.8±31.0 °C at 760 mmHg | |
Molecular Formula | C10H20N2O2 | Melting Point | 162-166 °C(lit.) | |
MSDS | Chinese USA | Flash Point | 138.2±24.8 °C | |
Symbol |
GHS07 |
Signal Word | Warning |
Discovery of a piperidine-4-carboxamide CCR5 antagonist (TAK-220) with highly potent Anti-HIV-1 activity.
J. Med. Chem. 49 , 2784, (2006) We incorporated various polar groups into previously described piperidine-4-carboxamide CCR5 antagonists to improve their metabolic stability in human hepatic microsomes. Introducing a carbamoyl group into the phenyl ring of the 4-benzylpiperidine moiety affo... |
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Synthesis of potent oxindole CDK2 inhibitors.
Bioorg. Med. Chem. 11 , 1873-1881, (2003) A series of oxindole CDK2 inhibitors was synthesized. These novel analogues have a saturated monosubstituted cyclic moiety at their C-4 position that mimics the ribofuranoside of ATP. This substitution afforded agents with increased potency relative to the pa... |
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Poly (2-isopropyl-2-oxazoline)-poly (L-glutamate) block copolymers through ammonium-mediated NCA polymerization. Meyer M and Schlaad H.
Macromolecules 39(11) , 3967-3970, (2006)
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