Anthranilic acid

Anthranilic acid Structure
Anthranilic acid structure
Common Name Anthranilic acid
CAS Number 118-92-3 Molecular Weight 137.136
Density 1.3±0.1 g/cm3 Boiling Point 311.9±25.0 °C at 760 mmHg
Molecular Formula C7H7NO2 Melting Point 144-148 °C(lit.)
MSDS Chinese USA Flash Point 142.4±23.2 °C
Symbol GHS07
GHS07
Signal Word Warning

Toxicological assessment and management options for boat pressure-washing wastewater.

Ecotoxicol. Environ. Saf. 114 , 164-70, (2015)

Boats are washed periodically for maintenance in order to remove biofoulants from hulls, which results in the generation of wastewater. This study aimed at evaluating the cyto/genotoxic and mutagenic properties of wastewater produced by pressure washing of bo...

Development of a quantitative mass spectrometry multi-attribute method for characterization, quality control testing and disposition of biologics.

MAbs 7 , 881-90, (2015)

Regulatory agencies have recently recommended a Quality by Design (QbD) approach for the manufacturing of therapeutic molecules. A QbD strategy requires deep understanding at the molecular level of the attributes that are crucial for safety and efficacy and f...

Coformer screening using thermal analysis based on binary phase diagrams.

Pharm. Res. 31(8) , 1946-57, (2014)

The advent of cocrystals has demonstrated a growing need for efficient and comprehensive coformer screening in search of better development forms, including salt forms. Here, we investigated a coformer screening system for salts and cocrystals based on binary...

Stable isotopic labeling-based quantitative targeted glycomics (i-QTaG).

Biotechnol. Prog. 31 , 840-8, (2015)

Mass spectrometry (MS) analysis combined with stable isotopic labeling is a promising method for the relative quantification of aberrant glycosylation in diseases and disorders. We developed a stable isotopic labeling-based quantitative targeted glycomics (i-...

Comparative studies of N-glycans and glycosaminoglycans present in SIRC (Statens Seruminstitut rabbit cornea) cells and corneal epithelial cells from rabbit eyes.

Curr. Eye Res. 39(7) , 686-94, (2014)

We compared cultured Statens Seruminstitut rabbit cornea (SIRC) cells and corneal epithelial cells from rabbit eyes by analyzing their N-glycans and glycosaminoglycans (GAGs). This work is a fundamental study on the efficacy of using cultured cells instead of...

Discrimination of isobaric Leu/Ile residues by MALDI in-source decay mass spectrometry.

J. Am. Soc. Mass Spectrom. 24(2) , 297-300, (2013)

MALDI in-source decay (ISD) has been used for top-down sequencing of proteins. The use of the matrix 1,5-diaminonapthalene (1,5-DAN) gave abundant w ions, which are formed from the unimolecular dissociation of z• radical fragments via α cleavage reaction and ...

Slow Off-rates and Strong Product Binding Are Required for Processivity and Efficient Degradation of Recalcitrant Chitin by Family 18 Chitinases.

J. Biol. Chem. 290 , 29074-85, (2015)

Processive glycoside hydrolases are the key components of enzymatic machineries that decompose recalcitrant polysaccharides, such as chitin and cellulose. The intrinsic processivity (P(Intr)) of cellulases has been shown to be governed by the rate constant of...

Systemic tryptophan and kynurenine catabolite levels relate to severity of rhinovirus-induced asthma exacerbation: a prospective study with a parallel-group design.

Thorax 68(12) , 1122-30, (2013)

Patients with allergic asthma have exacerbations which are frequently caused by rhinovirus infection. The antiviral tryptophan-catabolising enzyme indoleamine 2,3-dioxygenase (IDO) is induced by interferon-γ and suppressed by Th2 mediators interleukin (IL)-4 ...

Vitamin B1 deficiency inhibits the increased conversion of tryptophan to nicotinamide in severe food-restricted rats.

Biosci. Biotechnol. Biochem. 79(1) , 103-8, (2015)

The conversion of tryptophan (Trp) → nicotinamide (Nam) is an important pathway for supplying vitamin niacin. We reported the following two phenomena: (1) severe food restriction led to an increase in the Trp → Nam conversion compared with free-access control...

Time-dependent effects of L-tryptophan administration on urinary excretion of L-tryptophan metabolites.

J. Nutr. Sci. Vitaminol. 60(4) , 255-60, (2014)

We have previously reported that dietary supplementation with up to 5.0 g/d of L-tryptophan (L-Trp) for 21 d has no adverse effects, judging from the levels of general blood variables, in healthy women. We performed a randomized, double-blind, placebo-control...