Benzanilide
Benzanilide structure
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Common Name | Benzanilide | ||
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| CAS Number | 93-98-1 | Molecular Weight | 197.232 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 357.0±25.0 °C at 760 mmHg | |
| Molecular Formula | C13H11NO | Melting Point | 161-163 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 223.8±12.4 °C | |
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Benzanilides with spasmolytic activity: chemistry, pharmacology, and SAR.
Bioorg. Med. Chem. 16 , 5974-81, (2008) The following study describes the synthesis of new benzanilide derivatives and their pharmacological investigation on smooth muscle preparations of guinea pigs. All compounds were synthesized in good yields and showed a spasmolytic activity without significan... |
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Unusual spectral shifts on fast violet-B and benzanilide: Effect of solvents, pH and beta-cyclodextin.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 74(2) , 484-97, (2009) The absorption and fluorescence spectra of fast violet-B (FVB) and benzanilide (BA) have been analysed in different solvents, pH and beta-cyclodextrin. The inclusion complex of FVB with beta-CD is investigated by UV-visible, fluorimetry, AM 1, FTIR and SEM. T... |
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On the relationship between the substitution pattern of thiobenzanilides and their antimycobacterial activity.
Il Farmaco 57(9) , 777-82, (2002) The goal of this work was to shed more light on a preliminary finding about the relationship between the substitution in the thioacyl part of thiobenzanilides and their antituberculous effect. Thus, we prepared a set of 14 derivatives, out of which eight had ... |
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Dual fluorescence of diphenyl carbazide and benzanilide: effect of solvents and pH on electronic spectra.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 62(4-5) , 991-9, (2005) The absorption and fluorescence spectra of benzanilide (BA) and diphenyl carbazide (DPC) in solvents of different polarities and pH have been analysed. The spectral characteristics of DPC and BA are compared with diphenyl amine molecule. In water and methanol... |
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New amido derivatives as potential BKCa potassium channel activators. XI.
Eur. J. Med. Chem. 43(4) , 792-9, (2008) The vasorelaxing effects of exogenous activators of large-conductance calcium-activated potassium channels (BK channels) can furnish the pharmacological rational basis for the treatment of hypertension and/or other diseases related with an impaired contractil... |
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Joint QSAR analysis using the Free-Wilson approach and quantum chemical parameters.
SAR QSAR Environ. Res. 12(5) , 471-9, (2001) A new quantitative structure-activity relationship (QSAR) technique combining the Free-Wilson method and constructed quantum chemical parameters was used to simulate the aqueous solubility (Sw), 1-octanol/water partition coefficient (Kow) of 14 new synthesize... |
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Determination of a benzamide histone deacetylase inhibitor, MS-275, in human plasma by liquid chromatography with mass-spectrometric detection
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 877(3) , 355-9, (2009) An analytical method was developed and validated for the quantitative determination of the histone deacetylase inhibitor MS-275 in human plasma. Calibration curves were linear in the concentration range of 1–250 ng/mL. Sample pretreatment involved a liquid–li... |
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Enantioseparation of benzazoles and benzanilides on polysaccharide-based chiral columns.
Chirality 22(4) , 382-8, (2010) The chiral recognition ability of the polysaccharide-based chiral columns (Chiralpak AD-RH, Chiralpak AS-RJ, Chiralpak IC, Chiralcel OD-RH, and Chiralcel OJ-RH) for the benzazoles and the benzanilides was evaluated under reversed phase conditions. The columns... |
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N-Methylbenzanilide derivatives as a novel class of selective V(1A) receptor antagonists.
Bioorg. Med. Chem. Lett. 12(2) , 229-32, (2002) During our efforts to develop a novel class of selective V(1A) receptor antagonists, the N-methylbenzanilide structure was applied to a 4,4-difluoro-1-benzazepine derivative, 4, which is a selective V(1A) receptor antagonist. Further structural modifications ... |
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Thermodynamic interactions of a cis and trans benzanilide with Escherichia coli bacterial membranes.
Eur. Biophys. J. 41(8) , 687-93, (2012) The activity of a membrane interactive cis and trans benzanilide against Escherichia coli membrane mimics was investigated using Langmuir monolayers. It was found that in the presence of E. coli lipid mix monolayers, cis-benzanilide induced maximal surface pr... |