6-bromo-3-formylchromone

6-bromo-3-formylchromone Structure
6-bromo-3-formylchromone structure
Common Name 6-bromo-3-formylchromone
CAS Number 52817-12-6 Molecular Weight 253.04900
Density 1.835g/cm3 Boiling Point 365.7ºC at 760 mmHg
Molecular Formula C10H5BrO3 Melting Point 190-193 °C(lit.)
MSDS Chinese USA Flash Point 175ºC
Symbol GHS07
GHS07
Signal Word Warning

Discovery of new chromone containing sulfonamides as potent inhibitors of bovine cytosolic carbonic anhydrase.

Bioorg. Med. Chem. 19 , 3367-71, (2011)

Series of chromone containing sulfonamides were prepared by the reaction of (un)substituted 3-formylchromones with 3-aminobenzenesulfonamide and 4-aminobenzenesulfonamide. Bovine carbonic anhydrase (bCA) inhibitory activity of these newly synthesized compound...

Multidrug resistance reversal by 3-formylchromones in human colon cancer and human mdr1 gene-transfected mouse lymphoma cells.

In Vivo 20(5) , 645-9, (2006)

Several new 3-formylchromone derivatives proved to be modifiers of multidrug resistance in mouse lymphoma cells and in human Colo320 colon cancer cells. There is apparently a structure-activity relationship between the antiproliferative multidrug resistance-r...

Biological activity of 3-formylchromones and related compounds.

In Vivo 21(5) , 829-34, (2007)

Several 3-formylchromone derivatives were examined for their tumor cell-cytotoxic, anti-Helicobacter pylori, urease inhibitory and anti-HIV activity. Comparing their relative cytotoxicity against four human tumor cell lines and three normal human cells, tumor...

A study of the reactions of 2-aryl-4-hydroxy-6H-1,3-thiazin-6-ones with chromone-3-carboxaldehydes. Shutov RV, et al.

Tetrahedron Lett. 52(2) , 266-269, (2011)