DBCO-Amine

DBCO-Amine Structure
DBCO-Amine structure
Common Name DBCO-Amine
CAS Number 1255942-06-3 Molecular Weight 276.33200
Density N/A Boiling Point N/A
Molecular Formula C18H16N2O Melting Point N/A
MSDS Chinese USA Flash Point N/A

Rapid Cu-free click chemistry with readily synthesized biarylazacyclooctynones.

J. Am. Chem. Soc. 11th ed., 132 , 3688-3690, (2010)

Bioorthogonal chemical reactions, those that do not interact or interfere with biology, have allowed for exploration of numerous biological processes that were previously difficult to study. The reaction of azides with strained alkynes, such as cyclooctynes, ...

Copper-free click chemistry for dynamic in vivo imaging.

Proc. Natl. Acad. Sci. U. S. A. 43th ed., 104 , 16793-16797, (2007)

Dynamic imaging of proteins in live cells is routinely performed by using genetically encoded reporters, an approach that cannot be extended to other classes of biomolecules such as glycans and lipids. Here, we report a Cu-free variant of click chemistry that...

Visualizing metabolically labeled glycoconjugates of living cells by copper-free and fast huisgen cycloadditions.

Angew. Chem. Int. Ed. Engl. 47 , 2253-2255, (2008)

A comparative study of bioorthogonal reactions with azides.

ACS Chem. Biol. 10th ed., 1 , 644-648, (2006)

Detection of metabolites and post-translational modifications can be achieved using the azide as a bioorthogonal chemical reporter. Once introduced into target biomolecules, either metabolically or through chemical modification, the azide can be tagged with p...