Neuraminidase
Neuraminidase structure
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Common Name | Neuraminidase | ||
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| CAS Number | 9001-67-6 | Molecular Weight | 226.232 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 656.2±55.0 °C at 760 mmHg | |
| Molecular Formula | C9H14N4O3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 350.7±31.5 °C | |
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Neuraminidase inhibitors for influenza: a review and public health perspective in the aftermath of the 2009 pandemic.
Influenza Other Respi. Viruses 7 Suppl 1 , 14-24, (2013) The objectives of this study were to: (1) reflect on key stages in the discovery, development and pre-pandemic use of neuraminidase inhibitors (NAIs), (2) summarise the evidence of NAI effectiveness for treatment and prophylaxis of seasonal influenza prior to... |
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Genetic ancestor of external antigens of pandemic influenza A/H1N1 virus.
Interdiscip. Sci. 4(4) , 282-90, (2012) The aim of the present investigation was to discover the genetic relationships of 2009 pandemic novel influenza A/H1N1 virus (NIV) external antigens Hemagglutinin (HA) and Neuraminidase (NA) with other influenza viruses by performing phylogenetic, comparative... |
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Nucleic acid-based detection of influenza A virus subtypes H7 and N9 with a special emphasis on the avian H7N9 virus.
Euro Surveill. 19(10) , (2014) In 2013, a novel influenza A virus of subtype H7N9 was transmitted from avian sources to humans in China, causing severe illness and substantial mortality. Rapid and sensitive diagnostic approaches are the basis of epidemiological studies and of utmost import... |
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Department of Health's misguided alert recommending neuraminidase inhibitors for flu.
BMJ 348 , g1594, (2014)
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A community cluster of influenza A(H1N1)pdm09 virus exhibiting cross-resistance to oseltamivir and peramivir in Japan, November to December 2013.
Euro Surveill. 19(1) , (2014) Six influenza A(H1N1)pdm09 viruses were detected in Sapporo, Japan, between November and December 2013. All six viruses possessed an H275Y substitution in the neuraminidase protein, which confers cross-resistance to oseltamivir and peramivir. No epidemiologic... |
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Cochrane researchers continue to face challenges over access to data on flu drugs.
BMJ 346 , f3190, (2013)
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IL-17-producing B cells combat parasites.
Nat. Immunol. 14(5) , 419-21, (2013)
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Some questions and suggestions on the type references of the official nomenclature (IUB) for sialidase(s) and endosialidase.
Biochem. J. 278 ( Pt 1) , 311-2, (1991)
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Structural analysis of the novel influenza A (H7N9) viral Neuraminidase interactions with current approved neuraminidase inhibitors Oseltamivir, Zanamivir, and Peramivir in the presence of mutation R289K.
BMC Bioinformatics 14 Suppl 16 , S7, (2013) Since late March 2013, there has been another global health concern with a sudden wave of flu infections by a novel strain of avian influenza A (H7N9) virus in China. To-date, there have been more than 100 infections with 23 deaths. It is more worrying as thi... |
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Modulation of an ectodomain motif in the influenza A virus neuraminidase alters tetherin sensitivity and results in virus attenuation in vivo.
J. Mol. Biol. 426(6) , 1308-21, (2014) We previously demonstrated that ectodomain residue Asp286 in N2 neuraminidase (NA; Asp268 in N1 NA) present in budding-capable NA proteins contributes to productive NA plasma membrane transport partly by mediating escape from tetherin restriction [Yondola MA,... |