Bicyclo[2.2.1]hept-5-ene-2-acetic acid, 2,5-dioxo-1-pyrrolidinyl ester structure
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Common Name | Bicyclo[2.2.1]hept-5-ene-2-acetic acid, 2,5-dioxo-1-pyrrolidinyl ester | ||
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CAS Number | 1234203-45-2 | Molecular Weight | 249.262 | |
Density | 1.3±0.1 g/cm3 | Boiling Point | 369.8±25.0 °C at 760 mmHg | |
Molecular Formula | C13H15NO4 | Melting Point | 115-120°C | |
MSDS | USA | Flash Point | 177.4±23.2 °C | |
Symbol |
GHS07 |
Signal Word | Warning |
Tetrazine-based cycloadditions: application to pretargeted live cell imaging.
Bioconjug. Chem. 19 , 2297-2299, (2008) Bioorthogonal tetrazine cycloadditions have been applied to live cell labeling. Tetrazines react irreversibly with the strained dienophile norbornene forming dihydropyrazine products and dinitrogen. The reaction is high yielding, selective, and fast in aqueou... |
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Development of a bioorthogonal and highly efficient conjugation method for quantum dots using tetrazine-norbornene cycloaddition.
J. Am. Chem. Soc. 132 , 7838-7839, (2010) We present a bioorthogonal and modular conjugation method for efficient coupling of organic dyes and biomolecules to quantum dots (QDs) using a norbornene-tetrazine cycloaddition. The use of noncoordinating functional groups combined with the rapid rate of th... |
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