2,5-Dibromobenzenesulfonyl chloride

2,5-Dibromobenzenesulfonyl chloride Structure
2,5-Dibromobenzenesulfonyl chloride structure
Common Name 2,5-Dibromobenzenesulfonyl chloride
CAS Number 23886-64-8 Molecular Weight 334.413
Density 2.1±0.1 g/cm3 Boiling Point 364.4±32.0 °C at 760 mmHg
Molecular Formula C6H3Br2ClO2S Melting Point 69-73 °C(lit.)
MSDS Chinese USA Flash Point 174.2±25.1 °C
Symbol GHS05
GHS05
Signal Word Danger

Palladium-catalyzed direct desulfitative C2 arylations of 3-halo-N-protected indoles using (hetero)arenesulfonyl chlorides.

Org. Biomol. Chem. 14(21) , 4947-56, (2016)

The direct arylation of N-protected 3-haloindole derivatives with benzenesulfonyl chlorides as coupling partners using 5 mol% of bis(acetonitrile)dichloropalladium(ii) catalyst and lithium carbonate as a base in 1,4-dioxane was investigated. We demonstrated t...

Discovery of novel cyanamide-based inhibitors of cathepsin C.

ACS Med. Chem. Lett. 2 , 142-147, (2011)

The discovery of potent and selective cyanamide-based inhibitors of the cysteine protease cathepsin C is detailed. Optimization of the template with regard to plasma stability led to the identification of compound 17, a potent cathepsin C inhibitor with excel...