5-nitropyrimidine-4,6-diol
5-nitropyrimidine-4,6-diol structure
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Common Name | 5-nitropyrimidine-4,6-diol | ||
|---|---|---|---|---|
| CAS Number | 2164-83-2 | Molecular Weight | 157.084 | |
| Density | 1.9±0.1 g/cm3 | Boiling Point | 303.5±37.0 °C at 760 mmHg | |
| Molecular Formula | C4H3N3O4 | Melting Point | >300 °C(lit.) | |
| MSDS | USA | Flash Point | 137.4±26.5 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Phenobarbital induction and chemical synergism demonstrate the role of UDP-glucuronosyltransferases in detoxification of naphthalophos by Haemonchus contortus larvae.
Antimicrob. Agents Chemother. 58(12) , 7475-83, (2014) We used an enzyme induction approach to study the role of detoxification enzymes in the interaction of the anthelmintic compound naphthalophos with Haemonchus contortus larvae. Larvae were treated with the barbiturate phenobarbital, which is known to induce t... |
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Inhibition of UDP-glucuronyltransferase activity in rat liver microsomes by pyrimidine derivatives.
Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. 112(3) , 321-5, (1995) Thirty-one differently substituted pyrimidine bases were tested for their inhibitory effect on the glucuronidation of 4-nitrophenol and phenolphthalein by rat liver microsomes. 5-Nitrouracil (compound 1) and its isomer 4,6-dihydroxy-5-nitropyrimidine (compoun... |
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The activity of thymidine phosphorylase obtained from human uterine leiomyomas and studied in the presence of pyrimidine derivatives.
Z. Naturforsch., C, J. Biosci. 52(9-10) , 670-5, (1997) Partially purified samples of thymidine phosphorylase were obtained from four preparations of human uterine leiomyomas and uteri using the method of Yoshimura et al. (1990), Biochim. Biophys. Acta 1034, 107-113. Among the studied twelve pyrimidine derivatives... |