1-Methyl-2-nitroguanidine
1-Methyl-2-nitroguanidine structure
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Common Name | 1-Methyl-2-nitroguanidine | ||
|---|---|---|---|---|
| CAS Number | 4245-76-5 | Molecular Weight | 118.095 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 177.3±23.0 °C at 760 mmHg | |
| Molecular Formula | C2H6N4O2 | Melting Point | 153-155 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 61.0±22.6 °C | |
| Symbol |
GHS02, GHS07 |
Signal Word | Danger | |
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Development of immunoassay based on monoclonal antibody reacted with the neonicotinoid insecticides clothianidin and dinotefuran.
Sensors (Basel.) 12(11) , 15858-72, (2012) Enzyme-linked immunosorbent assay (ELISA) based on a monoclonal antibody (MoAb) was developed for the neonicotinoid insecticide clothianidin. A new clothianidin hapten (3-[5-(3-methyl-2-nitroguanidinomethyl)-1,3-thiazol-2-ylthio] propionic acid) was synthesiz... |
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Multiple-endpoint mutagenesis with Chinese hamster ovary (CHO) cells: evaluation with eight carcinogenic and non-carcinogenic compounds.
Mol. Toxicol. 1(2-3) , 217-34, (1987) Previously, we have shown that Chinese hamster ovary (CHO) cells are useful for quantifying chemical-induced gene mutations. We have defined the conditions of a Multiplex CHO System which permits determination of mutagen-induced chromosome aberration, and sis... |
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Hydroxyl free radical production by the reaction of N-methyl-N'-nitro-N-nitrosoguanidine with hydrogen peroxide without exposure to light.
Biochem. Cell Biol. 70(3-4) , 262-8, (1992) We examined hydroxyl free radical (.OH) production in the mixture of H2O2 and N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) without exposure to light using the electron spin resonance spin-trapping technique. When the mixtures were protected from exposure to li... |
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Production of hydroxyl free radical in the xanthine oxidase system with addition of 1-methyl-3-nitro-1-nitrosoguanidine.
Free Radic. Res. 36(6) , 641-7, (2002) We have examined the mechanism of 1-methyl-3-nitro-1-nitrosoguanidine (MNNG)-induced gastric cancer with respect to the production of hydroxyl free radical (OH). Nucleophilic attack by H2O2 on the nitroso group of MNNG produces 1-methyl-3-nitroguanidine (MNG)... |
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N-methyl-N'-nitroguanidine: irritation, sensitization, and acute oral toxicity, genotoxicity, and methods for analysis in biological samples.
Toxicol. Ind. Health 9(3) , 457-77, (1993) Currently, N-methyl-N'-nitroguanidine (MNG) is being considered by the U.S. Air Force Armament Laboratory for use in explosive formulations. A mammalian toxicity profile has been performed which includes the analysis of chemical impurities and an assessment o... |
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TNF-induced necroptosis and PARP-1-mediated necrosis represent distinct routes to programmed necrotic cell death.
Cell. Mol. Life Sci. 71(2) , 331-48, (2014) Programmed necrosis is important in many (patho)physiological settings. For specific therapeutic intervention, however, a better knowledge is required whether necrosis occurs through one single "core program" or through several independent pathways. Previousl... |
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Isolation and characterization of a cold-induced nonculturable suppression mutant of Vibrio vulnificus.
Microbiol. Res. 162(2) , 130-8, (2007) The viable but nonculturable (VBNC) suppression mutant formed platable cells at low temperature stress after inoculation in artificial seawater (ASW). Suppression subtractive hybridization was used to identify differentially expressed genes among cDNAs of the... |
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Improvement of fungal strain by repeated and sequential mutagenesis and optimization of solid state fermentation for the hyper-production of raw-starch-digesting enzyme.
J. Microbiol. Biotechnol. 20(4) , 718-26, (2010) A selected fungal strain, for production of the raw-starchdigesting enzyme by solid-state fermentation, was improved by two repeated sequential exposures to gamma-irradiation of Co60, ultraviolet, and four repeated treatments with Nmethyl- N'-nitrosoguanidine... |