Felypressin structure
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Common Name | Felypressin | ||
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CAS Number | 56-59-7 | Molecular Weight | 1040.219 | |
Density | 1.3±0.1 g/cm3 | Boiling Point | 1571.3±65.0 °C at 760 mmHg | |
Molecular Formula | C46H65N13O11S2 | Melting Point | 254-257 °C | |
MSDS | Chinese USA | Flash Point | 904.1±34.3 °C |
Ex vivo correlation of the permeability of metoprolol across human and porcine buccal mucosa.
J. Pharm. Sci. 103(7) , 2053-61, (2014) The pH partition theory proposes a correlation between fraction of unionized drug substance and permeability. The aim of this study was to compare the permeability of metoprolol and mannitol in ex vivo human and porcine buccal mucosa models at varying pH to v... |
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Intraoperative local anaesthesia for reduction of postoperative pain following general anaesthesia for dental treatment in children and adolescents.
Cochrane Database Syst. Rev. 12 , CD009742, (2014) Whilst carrying out dental procedures under general anaesthesia (GA), practitioners routinely give local anaesthetics (LA) intraoperatively to children. Local anaesthetics are used to help manage postoperative pain and reduce bleeding and the physiological re... |
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Octopus, which owns the most advanced brain in invertebrates, has two members of vasopressin/oxytocin superfamily as in vertebrates.
Regul. Pept. 115(2) , 139-49, (2003) A novel member of the vasopressin/oxytocin superfamily, octopressin (OP), has been isolated from Octopus vulgaris. Since another peptide of this superfamily, cephalotocin (CT), was isolated from the same species [Neurosci. Lett. 134 (1992) 191], Octopus has t... |
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Effects of dental local anaesthetics in cardiac transplant recipients.
Br. Dent. J. 192(3) , 161-3, (2002) To investigate the cardiovascular responses of cardiac transplant recipients to dental local anaesthetic solutions with and without epinephrine (adrenaline).A clinical study employing 30 patients (20 cardiac transplant recipients and ten healthy) awaiting gin... |
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Clinical and radiographic evaluation of pulpotomies performed under intrapulpal injection of anaesthetic solution.
Int. Endod. J. 34(6) , 440-6, (2001) The purpose of this study was to evaluate clinically and radiographically pulpotomies carried out under intrapulpal injection of anaesthetic solution.Forty-one permanent mandibular molar teeth presenting with deep carious lesions and/or exposed pulps, with or... |
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Comparison of the effect of lidocaine-epinephrine and prilocaine-felypressine to alter macrophage functions.
Int. Immunopharmacol. 1(5) , 911-23, (2001) In vitro treatment of macrophages with lidocaine-epinephrine or prilocaine-felypressine resulted in inhibition of their adhesion, chemotaxis and phagocytosis. However, prilocaine-felypressine was a much more potent inhibitor of adhesion and phagocytosis than ... |
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Effects of vasoconstrictors used in local anesthesia upon isolated rat heart.
Pharmacol. Res. 46(1) , 15-8, (2002) Some reports have demonstrated that the vasoconstrictor effect of catecholamines may be amplified by felypressin. Thus, the association of felypressin and epinephrine with local anesthetics may be indicated to achieve more effective vasoconstrictor actions wi... |
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Verification of protector effect of the norepinephrine and felypressin upon the cardiovascular system under action of the lidocaine hydrochloride and prilocaine hydrochloride in anesthetized rats.
Pharmacol. Res. 46(2) , 107-11, (2002) Vasoconstrictor substances, as norepinephrine and epinephrine, were mixtured to local anesthetics to decrease their toxic effects and to prolong the depth of the anesthesia. However, these catecholamines produce systolic and diastolic hypertension. The effect... |
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Effects of the prilocaine and of the association of prilocaine with different vasoconstrictors on the isolated hearts of rats.
Pharmacol. Res. 48(4) , 325-8, (2003) This study aimed to observe the effects of prilocaine chloridate (P) and the associations of P with felypressin (P+F), and epinephrine (P+E) on the heart rate and force of contraction on the isolated hearts of rats. The hearts were perfused according to Lange... |
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Effects of local injection of prilocaine-felypressin on the myocardial oxygen balance in dogs.
Eur. J. Oral Sci. 111(4) , 339-45, (2003) The authors investigated the effects of felypressin (Fely), a non-adrenergic vasoconstrictor, used together with prilocaine on myocardial oxygen balance. Six open-chest dogs were studied under urethane and alpha-chloralose anesthesia. Systolic arterial pressu... |