Polyacrylic acid

Polyacrylic acid Structure
Polyacrylic acid structure
Common Name Polyacrylic acid
CAS Number 9003-01-4 Molecular Weight 2000(Average)
Density 1.09 (30% aq.) Boiling Point 116ºC
Molecular Formula (C3H4O2)x Melting Point 106ºC
MSDS Chinese USA Flash Point 61.6ºC
Symbol GHS08
GHS08
Signal Word Danger

Cyclodextrin-crosslinked poly(acrylic acid): adhesion and controlled release of diflunisal and fluconazole from solid dosage forms.

AAPS PharmSciTech 14(1) , 301-11, (2013)

The controlled release of diflunisal and fluconazole from tablets made of novel polymers, poly(acrylic acid) (PAA) crosslinked with either β-cyclodextrin (βCD) or hydroxypropyl-βCD (HPβCD), was investigated and Carbopol 934P (Carbopol) was used as a highly cr...

Cyclodextrin-crosslinked poly(acrylic acid): Synthesis, physicochemical characterization and controlled release of diflunisal and fluconazole from hydrogels.

Int. J. Pharm. 444(1-2) , 175-84, (2013)

The aim of this work was to develop mucoadhesive hydrogels with variable drug delivery properties by crosslinking poly(acrylic acid) (PAA) with cyclodextrins (CDs). CD-PAA polymers with high CD content and good inter-batch reproducibility were synthesized by ...

Chest wall reconstruction using biomaterials.

Ann. Thorac. Surg. 95(3) , 1050-6, (2013)

Skeletal chest wall reconstruction can be a challenge, depending on the indication, location, and health of the patient; various materials are available. Recently, biomaterials that are remodelable (bovine pericardium patch; Veritas, Synovis Life Technologies...

Multifunctional magnetic-fluorescent eccentric-(concentric-Fe₃O₄@SiO₂@polyacrylic acid core-shell nanocomposites for cell imaging and pH-responsive drug delivery.

Nanoscale 5(6) , 2249-53, (2013)

Multifunctional fluorescent-magnetic pH-responsive eccentric-(concentric-Fe3O4@SiO2)@polyacrylic acid core-double shell nanocomposites (NCs) have been prepared for simultaneous cell imaging and pH-responsive drug delivery. To confirm the universality of the s...

Glycopolymer micelles with reducible ionic cores for hepatocytes-targeting delivery of DOX.

Int. J. Pharm. 441(1-2) , 170-80, (2013)

A novel galactose-decorated cross-linked micelles (cl-micelles) with ionic cores using cystamine (Cys) as a biodegradable cross-linker was prepared by using block ionomer complexes of poly(ethylene glycol)-b-poly(2-acryloxyethyl-galactose)-b-poly(acrylic acid...

Microwave-assisted synthesis of biocompatible europium-doped calcium hydroxyapatite and fluoroapatite luminescent nanospindles functionalized with poly(acrylic acid).

Langmuir 29(6) , 1985-94, (2013)

Europium-doped calcium hydroxyapatite and fluoroapatite nanophosphors functionalized with poly(acrylic acid) (PAA) have been synthesized through a one-pot microwave-assisted hydrothermal method from aqueous basic solutions containing calcium nitrate, sodium p...

Poly(acrylic acid)-grafted fluoropolymer films for highly sensitive fluorescent bioassays.

ACS Appl. Mater. Interfaces 5(6) , 2155-60, (2013)

In this study, a facile and effective method for the surface functionalization of inert fluoropolymer substrates using surface grafting was demonstrated for the preparation of a new platform for fluorescence-based bioassays. The surface of perfluorinated poly...

Surface functionality as a means to impact polymer nanoparticle size and structure.

Langmuir 29(12) , 4092-5, (2013)

When polymeric nanoparticles (NPs) are formed by nanoprecipitation, which is a nucleation-growth process, the control over size requires changing the polymer concentration or solvent composition. Here, we demonstrate that the NP size can be controlled indepen...

PAA-PAMPS copolymers as an efficient tool to control CaCO3 scale formation.

Langmuir 29(9) , 3080-8, (2013)

Scale formation, the deposition of certain minerals such as CaCO3, MgCO3, and CaSO4·2H2O in industrial facilities and household devices, leads to reduced efficiency or severe damage. Therefore, incrustation is a major problem in everyday life. In recent years...

DNA duplex stabilization in crowded polyanion solutions.

Chem. Commun. (Camb.) 49(13) , 1306-8, (2013)

The melting temperature of duplex DNA is much higher in polyanions than in non-ionic polymers with similar ionic strength, suggesting an additional electrostatic contribution on top of the excluded volume effect.