n6-methyl-2'-deoxy-adenosine
n6-methyl-2'-deoxy-adenosine structure
|
Common Name | n6-methyl-2'-deoxy-adenosine | ||
|---|---|---|---|---|
| CAS Number | 2002-35-9 | Molecular Weight | 265.27 | |
| Density | 1.72g/cm3 | Boiling Point | 603.6ºC at 760mmHg | |
| Molecular Formula | C11H15N5O3 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 318.8ºC | |
|
Activation of P2Y6 receptors increases the voiding frequency in anaesthetized rats by releasing ATP from the bladder urothelium.
Br. J. Pharmacol. 171(14) , 3404-19, (2014) Despite the abundant expression of the UDP-sensitive P2Y6 receptor in urothelial cells and sub-urothelial myofibroblasts its role in the control of bladder function is not well understood.We compared the effects of UDP and of the selective P2Y6 receptor agoni... |
|
|
GABA-mediated modulation of ATP-induced intracellular calcium responses in nodose ganglion neurons of the rat.
Neurosci. Lett. 584 , 168-72, (2014) We examined ATP-induced intracellular Ca(2+) ([Ca(2+)]i) responses in the neurons and satellite cells from one of the viscerosensory ganglia, the nodose ganglion (NG), as well as the GABA-mediated modulation of ATP-induced neuronal [Ca(2+)]i responses using i... |
|
|
Pharmacological characterization of the human P2Y13 receptor.
Mol. Pharmacol. 64 , 104-112, (2003) The P2Y13 receptor has recently been identified as a new P2Y receptor sharing a high sequence homology with the P2Y12 receptor as well as similar functional properties: coupling to Gi and responsiveness to ADP (Communi et al., 2001). In the present study, the... |
|
|
Competitive and selective antagonism of P2Y1 receptors by N6-methyl 2'-deoxyadenosine 3',5'-bisphosphate.
Br. J. Pharmacol. 124 , 1-3, (1998) The antagonist activity of N6-methyl 2'-deoxyadenosine 3',5'-bisphosphate (N6MABP) has been examined at the phospholipase C-coupled P2Y1 receptor of turkey erythrocyte membranes. N6MABP antagonized 2MeSATP-stimulated inositol phosphate hydrolysis with a poten... |
|
|
In vitro alkylation of calf thymus DNA by acrylonitrile. Isolation of cyanoethyl-adducts of guanine and thymine and carboxyethyl-adducts of adenine and cytosine.
Chem. Biol. Interact. 51 , 167-190, (1984) Reaction of the rodent carcinogen acrylonitrile (AN) at pH 5.0 and/or pH 7.0 for 10 and/or 40 days with 2'-deoxyadenosine (dAdo), 2'-deoxycytidine (dCyd), 2'-deoxyguanosine (dGuo), 2'-deoxyinosine (dIno), N6-methyl-2'-deoxyadenosine (N6-Me-dAdo) and thymidine... |
|
|
Supersensitivity of P2X receptors in cerebrocortical cell cultures after in vitro ischemia.
J. Neurochem. 95(5) , 1421-37, (2005) Neuronally enriched primary cerebrocortical cultures were exposed to glucose-free medium saturated with argon (in vitro ischemia) instead of oxygen (normoxia). Ischemia did not alter P2X7 receptor mRNA, although serum deprivation clearly increased it. Accordi... |
|
|
Comparison of the effects of N6-methyldeoxyadenosine and N5-methyldeoxycytosine on transcription from nuclear gene promoters in barley.
Plant J. 7(2) , 221-33, (1995) Methylation of deoxycytosine residues in plant nuclear DNA at CpG dinucleotides is generally assumed to suppress transcription, while deoxyadenosine methylation on recombinant reporter gene constructs transiently introduced into plant cells increases expressi... |