N-(3-Amino-4-methylphenyl)acetamide
N-(3-Amino-4-methylphenyl)acetamide structure
|
Common Name | N-(3-Amino-4-methylphenyl)acetamide | ||
|---|---|---|---|---|
| CAS Number | 6375-16-2 | Molecular Weight | 164.20400 | |
| Density | 1.109g/cm3 | Boiling Point | 645.4ºC at 760 mmHg | |
| Molecular Formula | C9H12N2O | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 213.5ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
|
Evidence for an acetoxyarylamine as the ultimate mutagenic reactive intermediate of the carcinogenic aromatic amine 2,4-diaminotoluene.
Mutat. Res. 242(2) , 101-10, (1990) 2,4-Diaminotoluene (2,4-DAT) is a mutagenic and hepatocarcinogenic aromatic amine, requiring metabolic activation. We have found that the mutagenic potency of 2,4-DAT in Salmonella TA98 is similar when activated by either Aroclor-1254-induced rat primary hepa... |
|
|
Comparison of the metabolism of 2,4-toluenediamine in rats and mice.
J. Environ. Pathol. Toxicol. 3(1-2) , 149-66, (1979) The excretion, distribution, and metabolism of 2,4-toluenediamine (TDA) have been compared in rats and mice. The elimination of TDA metabolites into urine was faster and more complete in mice than in rats. However, the feces of rats accounted for a greater pe... |
|
|
Gas chromatographic/tandem mass spectrometric identification and quantitation of metabolic 4-acetyltoluene-2,4-diamine from the F344 rat.
Biol. Mass Spectrom. 22(3) , 194-200, (1993) 2,4-Toluenediamine (TDA) and 2,4-toluenediisocyanate (TDI) are metabolized in the Fischer 344 rat to monoacetyl-2,4-toluenediamine (Ac-TDA) and diacetyl-2,4-toluenediamine (Ac2-TDA). A gas chromatographic/tandem mass spectrometric (GC/MS/MS) method was develo... |