1-(bis(4-fluorophenyl)methyl)piperazine

1-(bis(4-fluorophenyl)methyl)piperazine Structure
1-(bis(4-fluorophenyl)methyl)piperazine structure
Common Name 1-(bis(4-fluorophenyl)methyl)piperazine
CAS Number 27469-60-9 Molecular Weight 288.335
Density 1.2±0.1 g/cm3 Boiling Point 367.9±37.0 °C at 760 mmHg
Molecular Formula C17H18F2N2 Melting Point 88-92 °C(lit.)
MSDS N/A Flash Point 176.3±26.5 °C
Symbol GHS06
GHS06
Signal Word Danger

Oxidative metabolism of flunarizine in rat liver microsomes.

Res. Commun. Chem. Pathol. Pharmacol. 78(1) , 85-95, (1992)

The oxidative metabolism of flunarizine [1-[bis(4-fluorophenyl)-methyl]-4-(3-phenyl-2-propenyl)piperazine, FZ] to 1-[bis-(4-fluorophenyl)methyl]piperazine (M-1), 1-[bis(4-fluorophenyl)methyl]-4-[3-(4'-hydroxyphenyl)-2- propenyl]piperazine (M-2) and 4,4'-diflu...

Lipidosis of the dorsal root ganglia in rats treated with an almitrine metabolite.

Arch. Toxicol. 69(6) , 391-6, (1995)

Toxic effects of a detriazinyl metabolite of almitrine (DTMA) were evaluated in rats and on cultured rat macrophages. In rats daily treated with DTMA for 16 weeks, spastic gaits with heel-lifting appeared, and lamellated and/or crystalloid bodies formed in se...