Amprolium Hydrochloride

Amprolium Hydrochloride Structure
Amprolium Hydrochloride structure
Common Name Amprolium Hydrochloride
CAS Number 137-88-2 Molecular Weight 315.241
Density N/A Boiling Point N/A
Molecular Formula C14H20Cl2N4 Melting Point 241 °C
MSDS Chinese USA Flash Point N/A

Veterinary drug residues in domestic and imported foods of animal origin in the Republic of Korea.

Food. Addit. Contam. Part. B. Surveill. 8 , 106-12, (2015)

The Korean National Residue Programme comprises three different approaches for evaluating domestic and imported foods of animal origin: monitoring, surveillance/enforcement and an exploratory test programme. Monitoring and surveillance/enforcement testing pro...

Ethanol promotes thiamine deficiency-induced neuronal death: involvement of double-stranded RNA-activated protein kinase.

Alcohol. Clin. Exp. Res. 33(6) , 1097-103, (2009)

Heavy alcohol consumption causes cerebellar degeneration, and the underlying mechanism is unclear. Chronic alcoholism is usually associated with thiamine deficiency (TD) which is known to induce selective neurodegeneration in the brain. However, the role of T...

Determination of amprolium in feed by a liquid chromatography-mass spectrometry method.

J. Pharm. Biomed. Anal. 48(5) , 1457-61, (2008)

As a consequence of the finding of veterinarian drugs in food European Community banned several compounds like coccidiostats as amprolium (APL). This antibiotic has been used as a preventive and clinical anticoccidial drug in chicken. The 2005/187/CE, 2005/92...

Three thiamine analogues differently alter thiamine transport and metabolism in nervous tissue: an in vivo kinetic study using rats.

Metab. Brain Dis. 18(4) , 245-63, (2003)

Thiamine (T) analogues pyrithiamine, oxythiamine or amprolium in amounts 10-1000 times higher than labelled T, were i.p. injected into rats together with 14C-T (30 microg; 46.25 KBq). The radioactivity associated with T and its phosphoesters in the plasma and...

Acetyl-CoA metabolism in amprolium-evoked thiamine pyrophosphate deficits in cholinergic SN56 neuroblastoma cells.

Neurochem. Int. 59(2) , 208-16, (2011)

Inhibition of pyruvate (PDHC) and ketoglutarate (KDHC) dehydrogenase complexes induced by thiamine pyrophosphate deficits is known cause of disturbances of cholinergic transmission in the brain, yielding clinical symptoms of cognitive, vegetative and motor de...

Evaluation of a Bacillus stearothermophilus tube test as a screening tool for anticoccidial residues in poultry.

J. Vet. Sci. 7(2) , 177-80, (2006)

A Bacillus stearothermophilus var. calidolactis C953 tube test was evaluated for its ability in detecting the residue of selected anticoccidial drugs in poultry, specially sulfamethazine, furazolidone, and amprolium. Various concentrations of each drug were i...

Simplified high-performance liquid chromatographic determination of residual amprolium in edible chicken tissues.

J. Chromatogr. Sci. 40(7) , 355-8, (2002)

A simplified determining method for the routine monitoring of residual amprolium in edible chicken tissues (muscle and liver) is developed using a high-performance liquid chromatographic (HPLC) method with a photodiode-array detector after sample cleanup by a...

Simplified high-performance liquid chromatographic determination of residual amprolium in edible chicken tissues.

J. Chromatogr. Sci. 40(6) , 355-8, (2002)

A simplified determining method for the routine monitoring of residual amprolium in edible chicken tissues (muscle and liver) is developed using a high-performance liquid chromatographic (HPLC) method with a photodiode-array detector after sample cleanup by a...

Further studies on the spectrophotometric determination of amprolium.

J. AOAC Int. 87(3) , 677-80, (2004)

The official AOAC spectrophotometric analytical method for amprolium in feeds (961.24) is quantitatively selective for the intact drug in the presence of its primary degradation products. Concentrations evaluated included mixtures of the individual degradates...

A degenerative encephalomyelopathy in 7 Kuvasz puppies.

Can. Vet. J. 46(5) , 429-32, (2005)

Seven Kuvasz puppies from 2 same-parentage litters developed weakness and ataxia. Six necropsied dogs had lesions in caudate nucleus, cerebellar nuclei and folia, and spinal cord. Lesions seen were felt to be familial or due to the effects of an amprolium-ind...