6-chloro-3-formyl-7-methylchromone
6-chloro-3-formyl-7-methylchromone structure
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Common Name | 6-chloro-3-formyl-7-methylchromone | ||
|---|---|---|---|---|
| CAS Number | 64481-12-5 | Molecular Weight | 222.62400 | |
| Density | 1.485g/cm3 | Boiling Point | 380.9ºC at 760 mmHg | |
| Molecular Formula | C11H7ClO3 | Melting Point | 183-185 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 171.3ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Multidrug resistance reversal by 3-formylchromones in human colon cancer and human mdr1 gene-transfected mouse lymphoma cells.
In Vivo 20(5) , 645-9, (2006) Several new 3-formylchromone derivatives proved to be modifiers of multidrug resistance in mouse lymphoma cells and in human Colo320 colon cancer cells. There is apparently a structure-activity relationship between the antiproliferative multidrug resistance-r... |
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Small molecule inhibitors of mucin-type O-linked glycosylation from a uridine-based library.
Chem. Biol. 11(3) , 337-45, (2004) The polypeptide N-acetyl-alpha-galactosaminyltransferases (ppGalNAcTs, also abbreviated ppGaNTases) initiate mucin-type O-linked glycosylation and therefore play pivotal roles in cell-cell communication and protection of tissues. In order to develop new tools... |
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A simple and visible colorimetric method through Zr(4+)-phosphate coordination for the assay of protein tyrosine phosphatase 1B and screening of its inhibitors.
Analyst 140 , 5716-23, (2015) Inhibitors of protein tyrosine phosphatase 1B (PTP1B) are promising agents for the treatment of type 2 diabetes and obesity, so a colorimetric method has been developed in this work for PTP1B assay and screening of its inhibitors. The method is based on the c... |