2,3-Dimethylsuccinic acid
2,3-Dimethylsuccinic acid structure
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Common Name | 2,3-Dimethylsuccinic acid | ||
|---|---|---|---|---|
| CAS Number | 13545-04-5 | Molecular Weight | 146.141 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 241.9±13.0 °C at 760 mmHg | |
| Molecular Formula | C6H10O4 | Melting Point | 118-122ºC | |
| MSDS | Chinese USA | Flash Point | 114.4±16.3 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Mutagenic investigation of flavourings: dimethyl succinate, ethyl pyruvate and aconitic acid are negative in the Salmonella/mammalian-microsome test.
Food Addit. Contam. 1(3) , 283-8, (1984) Three flavourings: dimethyl succinate, ethyl pyruvate and aconitic acid, commonly used in candy, beverages, and baked goods, were tested in the Salmonella/mammalian-microsome test. Tester strains were TA 1535, TA 100, TA 1537 and TA 98 and doses were 32, 160,... |
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The substrate binding site of aldehyde reductase from pig liver. Stereochemical investigations using NADP--2-oxodiacid adducts as probe.
Eur. J. Biochem. 121(2) , 407-11, (1982) Aldehyde reductase I from pig liver is strongly inhibited by cyclized NADP--2-oxodiacid adducts. This result, in conjunction with those showing a strong inhibitory effect of certain diacid derivatives, such as (+/-)-dimethylsuccinic acid, towards aldehyde red... |
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Gem-dialkyl succinic acids: a novel class of inhibitors for carboxypeptidases.
Biochemistry 36(29) , 8710-5, (1997) gem-Dimethylsuccinic acid and its higher homolog, 2-methyl-2-ethylsuccinic acid (MESA) are highly potent inhibitors of both carboxypeptidase A (CPA) and B. The inhibition constant of MESA for CPA (0.11 microM for the racemic mixture) is remarkable considering... |
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The renal Na(+)-dependent dicarboxylate transporter, NaDC-3, translocates dimethyl- and disulfhydryl-compounds and contributes to renal heavy metal detoxification.
J. Am. Soc. Nephrol. 13(11) , 2628-38, (2002) The active transport of Krebs cycle intermediates, such as succinate, alpha-ketoglutarate, and citrate, is mediated by sodium-coupled transporters found in the luminal (NaDC-1) and basolateral plasma membranes (NaDC-3) of proximal tubule cells. This study use... |
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An oral treatment for lead toxicity.
Postgrad. Med. J. 67(783) , 63-5, (1991) Chronic lead poisoning has traditionally been treated by parenteral agents. We present a case where a comparison of ethylene diaminetetra-acetic acid was made with 2,3-dimethyl succinic acid (DMSA) which has the advantage of oral administration associated wit... |