all-cis-4,7,10,13,16-Docosapentaenoic acid, C22:5n6

all-cis-4,7,10,13,16-Docosapentaenoic acid, C22:5n6 Structure
all-cis-4,7,10,13,16-Docosapentaenoic acid, C22:5n6 structure
Common Name all-cis-4,7,10,13,16-Docosapentaenoic acid, C22:5n6
CAS Number 25182-74-5 Molecular Weight 330.50400
Density 0.932g/cm3 Boiling Point 443.8ºC at 760mmHg
Molecular Formula C22H34O2 Melting Point N/A
MSDS Chinese USA Flash Point 340.5ºC

Functional characterization of the duck and turkey fatty acyl elongase enzymes ELOVL5 and ELOVL2.

J. Nutr. 144(8) , 1234-9, (2014)

In most Western countries, the consumption of fish is low and insufficient to provide the recommended daily intake of the n-3 (ω-3) long-chain polyunsaturated fatty acids (PUFAs) eicosapentaenoic acid (EPA; 20:5n-3) and docosahexaenoic acid (DHA; 22:6n-3). Po...

Docosapentaenoic acid (DPA) is a critical determinant of cubic membrane formation in amoeba Chaos mitochondria.

FASEB J. 23(9) , 2866-71, (2009)

Very long-chain polyunsaturated fatty acids (VLC-PUFAs), such as docosahexaenoic acid (DHA) and docosapentaenoic acid (DPA), have recently made it to the realm of "magical molecules" based on their multiple presumably beneficial effects in biological systems,...

Reevaluation of the pathway for the metabolism of 7,10,13, 16-docosatetraenoic acid to 4,7,10,13,16-docosapentaenoic acid in rat liver.

Arch. Biochem. Biophys. 317(1) , 179-84, (1995)

When rat liver microsomes were incubated with [1-14C]22:4(n-6) under standard conditions for measuring acyl-CoA desaturases, it was not possible to detect the synthesis of any 22:5(n-6). When malonyl-CoA and NADPH were included in the incubation, 22:4(n-6) wa...

The metabolism of polyunsaturated fatty acids in rat Sertoli and germinal cells.

Lipids 15(6) , 389-94, (1980)

The metabolism of [1-14C] linoleic, [1-14C] arachidonic and [3-14C] docosa-4,7,10,13,16-pentaenoic acids was investigated after intratesticular injection of the labeled compounds and isolation of rat Sertoli and germinal cell. Following injection of either 14...

Dietary echium oil increases long-chain n-3 PUFAs, including docosapentaenoic acid, in blood fractions and alters biochemical markers for cardiovascular disease independently of age, sex, and metabolic syndrome.

J. Nutr. 144(4) , 447-60, (2014)

Dietary supplementation with echium oil (EO) containing stearidonic acid (SDA) is a plant-based strategy to improve long-chain (LC) n-3 (ω-3) polyunsaturated fatty acid (PUFA) status in humans. We investigated the effect of EO on LC n-3 PUFA accumulation in b...

Regulation of the biosynthesis of 4,7,10,13,16-docosapentaenoic acid.

Biochem. J. 326 ( Pt 2) , 425-30, (1997)

It is now established that fatty acid 7,10,13,16-22:4 is metabolized into 4,7,10,13,16-22:5 as follows: 7,10,13,16-22:4-->9,12,15, 18-24:4-->6,9,12,15,18-24:5-->4,7,10,13,16-22:5. Neither C24 fatty acid was esterified to 1-acyl-sn-glycero-3-phosphocholine (1-...