dimenhydrinate structure
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Common Name | dimenhydrinate | ||
---|---|---|---|---|
CAS Number | 523-87-5 | Molecular Weight | 469.96400 | |
Density | N/A | Boiling Point | 343.7ºC at 760 mmHg | |
Molecular Formula | C24H28ClN5O3 | Melting Point | 102-107ºC | |
MSDS | USA | Flash Point | 101.5ºC | |
Symbol |
GHS07 |
Signal Word | Warning |
Individualizing oral busulfan dose after using a test dose in patients undergoing hematopoietic stem cell transplantation: pharmacokinetic characterization.
Ther. Drug Monit. 37(1) , 66-70, (2015) Busulfan is an alkylating agent used for conditioning patients undergoing hematopoietic stem cell transplantation with a narrow therapeutic range and highly variable pharmacokinetics. High concentrations induce toxicity, especially hepatic veno-occlusive dise... |
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Nausea and vomiting in pregnancy: a review of the pathology and compounding opportunities.
Int. J. Pharm. Compd. 17(2) , 113-23, (2013) Nausea and vomiting in pregnancy can have serious adverse effects on the quality of a woman's life, affecting her occupational, social, and domestic functioning, and her general well-being; therefore, it is very important to treat this condition appropriately... |
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Mechanisms and abuse liability of the anti-histamine dimenhydrinate.
Neurosci. Biobehav. Rev. 26(1) , 61-7, (2002) The over-the-counter anti-emetic dimenhydrinate (DMH) (Gravol or Dramamine) has been reported to be abused for non-medicinal purposes. Street drug users abuse DMH for the acute effects of euphoric sensations and hallucinations, while psychiatric patients abus... |
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Vestibular suppressants after canalith repositioning in benign paroxysmal positional vertigo.
Laryngoscope 124(10) , 2400-3, (2014) To investigate the characteristics of residual symptoms and to evaluate the effects of adjuvant vestibular suppressants on residual symptoms after successful canalith repositioning procedures (CRPs).Individual randomized controlled trial.One hundred fifty pat... |
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Determination of sulphasalazine and its main metabolite sulphapyridine and 5-aminosalicylic acid in human plasma by liquid chromatography/tandem mass spectrometry and its application to a pharmacokinetic study.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 879(5-6) , 449-56, (2011) A simple and sensitive liquid chromatography/positive-ion electrospray ionization mass spectrometry (LC-ESI-MS/MS) method has been developed for the simultaneous determination of sulphasalazine (SASP) and its main metabolite sulphapyridine (SP) and 5-aminosal... |
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Antiemetics for acute gastroenteritis-related vomiting in children and adolescents.
Am. Fam. Physician 85(11) , 1054-6, (2012)
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Comparison of cinnarizine/dimenhydrinate fixed combination with the respective monotherapies for vertigo of various origins: a randomized, double-blind, active-controlled, multicentre study.
Clin. Drug Investig. 31(6) , 371-83, (2011) Vertigo may arise from dysfunction in the peripheral and/or the central vestibular system. Simultaneous activity of a medication at both sites will serve to improve the efficacy of antivertigo treatment. The aim of this study was to compare the efficacy and t... |
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[Vertigo in elderly patients. Early therapy chronification].
MMW Fortschr. Med. 153(46) , 52-3, (2011)
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[Vertigo. Evidence based therapy of dizziness].
MMW Fortschr. Med. 152(47) , 52-3, (2010)
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No effects of anti-motion sickness drugs on vestibular evoked myogenic potentials outcome parameters.
Otol. Neurotol. 32(3) , 497-503, (2011) To investigate the effects of meclizine (50 mg), baclofen (10 mg), cinnarizine (20 mg) + dimenhydrinate (40 mg), and promethazine (25 mg) + dextro-amphetamine (5 mg) on the parameters of the vestibular evoked myogenic potential (VEMP) test.Double-blind placeb... |