2,5-Difluorobenzyl bromide
2,5-Difluorobenzyl bromide structure
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Common Name | 2,5-Difluorobenzyl bromide | ||
|---|---|---|---|---|
| CAS Number | 85117-99-3 | Molecular Weight | 207.015 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 187.9±25.0 °C at 760 mmHg | |
| Molecular Formula | C7H5BrF2 | Melting Point | 8ºC | |
| MSDS | Chinese USA | Flash Point | 15.6±0.0 °C | |
| Symbol |
GHS02, GHS05 |
Signal Word | Danger | |
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Aryl sulfones: a new class of gamma-secretase inhibitors.
Bioorg. Med. Chem. Lett. 15(10) , 2685-8, (2005) The development of a novel series of 4-aryl, 4-phenylsulfonyl cyclohexananone-derived gamma-secretase inhibitors for the potential treatment of Alzheimer's disease is described. |
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Synthesis and evaluation of [(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]cyclohexanes and 4-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]piperidines as DPP-4 inhibitors.
Bioorg. Med. Chem. Lett. 21 , 1880-1886, (2011) A series of 4-amino cyclohexanes and 4-substituted piperidines were prepared and evaluated for inhibition of DPP-4. Analog 20q displayed both good DPP-4 potency and selectivity against other proteases, while derivative 20k displayed long half life and modest ... |
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