3-hydroxybutyric acid
3-hydroxybutyric acid structure
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Common Name | 3-hydroxybutyric acid | ||
|---|---|---|---|---|
| CAS Number | 300-85-6 | Molecular Weight | 104.104 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 269.2±0.0 °C at 760 mmHg | |
| Molecular Formula | C4H8O3 | Melting Point | 174-175℃ | |
| MSDS | Chinese USA | Flash Point | 121.0±19.1 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Cardiolipin profiles as a potential biomarker of mitochondrial health in diet-induced obese mice subjected to exercise, diet-restriction and ephedrine treatment.
J. Appl. Toxicol. 34(11) , 1122-9, (2014) Cardiolipin (CL) is crucial for mitochondrial energy metabolism and structural integrity. Alterations in CL quantity or CL species have been associated with mitochondrial dysfunction in several pathological conditions and diseases, including mitochondrial dys... |
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An improved method for the analysis of GHB in human hair by liquid chromatography tandem mass spectrometry.
J. Anal. Toxicol. 39(2) , 83-8, (2015) The abuse of gamma-hydroxybutyric acid (GHB) and its suspicion in cases of suspected drug-facilitated sexual assault is of keen interest to forensic toxicology laboratories. This paper reports an extraction, separation and detection procedure for GHB in hair ... |
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Physiology and pathophysiology of organic acids in cerebrospinal fluid.
J. Inherit. Metab. Dis. 16(4) , 648-69, (1993) Concentrations of organic acids in cerebrospinal fluid (CSF) appear to be directly dependent upon their rate of production in the brain. There is evidence that the net release of short-chain monocarboxylic acids from the brain is a major route for removing th... |
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The human serum metabolome.
PLoS ONE 6(2) , e16957, (2011) Continuing improvements in analytical technology along with an increased interest in performing comprehensive, quantitative metabolic profiling, is leading to increased interest pressures within the metabolomics community to develop centralized metabolite ref... |
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Age-related reference values for urinary organic acids in a healthy Turkish pediatric population.
Clin. Chem. 40(6) , 862-6, (1994) Organic acid concentrations were quantified by gas chromatography and the individual acids identified by mass spectrometry in urine specimens from a healthy Turkish pediatric population of ages 2 days to 16 years, subdivided into five age groups. We quantifie... |
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Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor.
Science 339(6116) , 211-4, (2013) Concentrations of acetyl-coenzyme A and nicotinamide adenine dinucleotide (NAD(+)) affect histone acetylation and thereby couple cellular metabolic status and transcriptional regulation. We report that the ketone body d-β-hydroxybutyrate (βOHB) is an endogeno... |
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Use of high-resolution proton nuclear magnetic resonance spectroscopy for rapid multi-component analysis of urine.
Clin. Chem. 30(3) , 426-32, (1984) Numerous low-Mr metabolites--including creatinine, citrate, hippurate, glucose, ketone bodies, and various amino acids--have been identified in 400- and 500-MHz proton nuclear magnetic resonance (1H NMR) spectra of intact human urine. The presence of many of ... |
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Association of ketone body levels with hyperglycemia and type 2 diabetes in 9,398 Finnish men.
Diabetes 62(10) , 3618-26, (2013) We investigated the association of the levels of ketone bodies (KBs) with hyperglycemia and with 62 genetic risk variants regulating glucose levels or type 2 diabetes in the population-based Metabolic Syndrome in Men (METSIM) study, including 9,398 Finnish me... |
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Automated screening of urine samples for carbohydrates, organic and amino acids after treatment with urease.
J. Chromatogr. A. 562(1-2) , 125-38, (1991) Eighty-five clinical urine samples and nineteen urine samples previously found by other laboratories to suggest genetic metabolic defects were prepared for trimethylsilylation by treatment with urease, followed by azeotropic dehydration. The "Target Analyte S... |
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Engineering cyanobacteria for photosynthetic production of 3-hydroxybutyrate directly from CO2.
Metab. Eng. 16 , 68-77, (2013) (S)- and (R)-3-hydroxybutyrate (3HB) are precursors to synthesize the biodegradable plastics polyhydroxyalkanoates (PHAs) and many fine chemicals. To date, however, their production has been restricted to petroleum-based chemical industry and sugar-based micr... |