Tetracycline
Tetracycline structure
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Common Name | Tetracycline | ||
|---|---|---|---|---|
| CAS Number | 60-54-8 | Molecular Weight | 444.435 | |
| Density | 1.3809 | Boiling Point | 554.44°C | |
| Molecular Formula | C22H24N2O8 | Melting Point | 175-177 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 432.0±32.9 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Stretch-stimulated glucose transport in skeletal muscle is regulated by Rac1.
J. Physiol. 593(3) , 645-56, (2015) Rac1 regulates stretch-stimulated (i.e. mechanical stress) glucose transport in muscle. Actin depolymerization decreases stretch-induced glucose transport in skeletal muscle. Rac1 is a required part of the mechanical stress-component of the contraction-stimul... |
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Glucose recognition proteins for glucose sensing at physiological concentrations and temperatures.
ACS Chem. Biol. 9(7) , 1595-602, (2014) Advancements in biotechnology have allowed for the preparation of designer proteins with a wide spectrum of unprecedented chemical and physical properties. A variety of chemical and genetic methods can be employed to tailor the protein's properties, including... |
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Cloning and Expression of TNF Related Apoptosis Inducing Ligand in Nicotiana tabacum.
Iran. J. Pharm. Res. 14(1) , 189-201, (2015) Molecular farming has been considered as a secure and economical approach for production of biopharmaceuticals. Human TNF Related Apoptosis Inducing Ligand (TRAIL) as a promising biopharmaceutical candidate has been produced in different expression hosts. How... |
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Septins arrange F-actin-containing fibers on the Chlamydia trachomatis inclusion and are required for normal release of the inclusion by extrusion.
MBio 5(5) , e01802-14, (2014) Chlamydia trachomatis is an obligate intracellular human pathogen that grows inside a membranous, cytosolic vacuole termed an inclusion. Septins are a group of 13 GTP-binding proteins that assemble into oligomeric complexes and that can form higher-order fila... |
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A substrate ambiguous enzyme facilitates genome reduction in an intracellular symbiont.
BMC Biol. 12 , 110, (2015) Genome evolution in intracellular microbial symbionts is characterized by gene loss, generating some of the smallest and most gene-poor genomes known. As a result of gene loss these genomes commonly contain metabolic pathways that are fragmented relative to t... |
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Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptor.
Nat. Commun. 5 , 5624, (2014) The earliest molecular events in T-cell recognition have not yet been fully described, and the initial T-cell receptor (TCR)-triggering mechanism remains a subject of controversy. Here, using total internal reflection/Forster resonance energy transfer microsc... |
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Mechanism of improved cellulosic bio-ethanol production from alfalfa stems via ambient-temperature acid pretreatment.
Bioresour. Technol. 193 , 288-96, (2015) Model compounds and recalcitrant biomass were studied to elucidate the mechanism of ambient-temperature acid pretreatment of cellulosic biomass for bio-ethanol production. Pure cellulose, a pure hemicellulose and alfalfa stems were pretreated with sulfuric ac... |
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Wee1 is required to sustain ATR/Chk1 signaling upon replicative stress.
Oncotarget 6 , 13072-87, (2015) The therapeutic efficacy of nucleoside analogues, e.g. gemcitabine, against cancer cells can be augmented by inhibitors of checkpoint kinases, including Wee1, ATR, and Chk1. We have compared the chemosensitizing effect of these inhibitors in cells derived fro... |
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KIF4A and PP2A-B56 form a spatially restricted feedback loop opposing Aurora B at the anaphase central spindle.
J. Cell Biol. 207(6) , 683-93, (2014) The mitotic kinase Aurora B is concentrated at the anaphase central spindle by the kinesin MKlp2 during mitotic exit and cytokinesis. This pool of Aurora B phosphorylates substrates including the kinesin KIF4A to regulate central spindle length. In this paper... |
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Hedgehog inhibitors from Artocarpus communis and Hyptis suaveolens.
Bioorg. Med. Chem. 23 , 4150-4, (2015) The hedgehog (Hh) signaling pathway plays crucial roles in cell maintenance and proliferation during embryonic development. Naturally occurring Hh inhibitors were isolated from Artocarpus communis and Hyptis suaveolens using our previously constructed cell-ba... |