Methyl 4-bromobenzoate

Methyl 4-bromobenzoate Structure
Methyl 4-bromobenzoate structure
Common Name Methyl 4-bromobenzoate
CAS Number 619-42-1 Molecular Weight 215.044
Density 1.5±0.1 g/cm3 Boiling Point 262.2±13.0 °C at 760 mmHg
Molecular Formula C8H7BrO2 Melting Point 77-81 °C(lit.)
MSDS Chinese USA Flash Point 112.4±19.8 °C
Symbol GHS07
GHS07
Signal Word Warning

Synthesis of classical, three-carbon-bridged 5-substituted furo[2,3-d]pyrimidine and 6-substituted pyrrolo[2,3-d]pyrimidine analogues as antifolates.

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Bridge homologation of the previously reported classical two-carbon-bridged antifolates, a 5-substituted 2,4-diaminofuro[2,3-d]pyrimidine (1) [which is a 6-regioisomer of LY231514 (Alimta)] and a 6-subsituted 2-amino-4-oxopyrrolo[2,3-d]pyrimidine, afforded th...

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